polynucleotide kinase-3'-phosphatase [Homo sapiens]

Run BLAST
Find regions of similarity between this sequence and other sequences using BLAST.
Identify Conserved Domains
View conserved domains detected in this protein sequence using CD-search.
Highlight Sequence Features
Opens the Highlight Feature Bar and highlights feature annotations from the FEATURES table of the record. The Highlight Feature Bar can be used to navigate to and highlight other features and provides links to display the highlighted region separately. Links in the FEATURES table will also highlight the corresponding region of the sequence. More...
Find in this Sequence
Finds sub-sequences or patterns in the sequence and highlights the matching regions. The tool works with standard single letter nucleotide or protein codes including ambiguities and can match Prosite patterns in protein sequences. More...

Site-specific acetylation of polynucleotide kinase 3'-phosphatase regulates its distinct role in DNA repair pathways. [Nucleic Acids Res. 2024]
Site-specific acetylation of polynucleotide kinase 3'-phosphatase regulates its distinct role in DNA repair pathways.
Islam A, Chakraborty A, Sarker AH, Aryal UK, Pan L, Sharma G, Boldogh I, Hazra T. Nucleic Acids Res. 2024 Mar 21; 52(5):2416-2433.
Functional analysis of a conserved site mutation in the DNA end processing enzyme PNKP leading to ataxia with oculomotor apraxia type 4 in humans. [J Biol Chem. 2023]
Functional analysis of a conserved site mutation in the DNA end processing enzyme PNKP leading to ataxia with oculomotor apraxia type 4 in humans.
Islam A, Chakraborty A, Gambardella S, Campopiano R, Sarker AH, Boldogh I, Hazra T. J Biol Chem. 2023 May; 299(5):104714. Epub 2023 Apr 13.
Zika Virus Induces Mitotic Catastrophe in Human Neural Progenitors by Triggering Unscheduled Mitotic Entry in the Presence of DNA Damage While Functionally Depleting Nuclear PNKP. [J Virol. 2022]
Zika Virus Induces Mitotic Catastrophe in Human Neural Progenitors by Triggering Unscheduled Mitotic Entry in the Presence of DNA Damage While Functionally Depleting Nuclear PNKP.
Rychlowska M, Agyapong A, Weinfeld M, Schang LM. J Virol. 2022 May 11; 96(9):e0033322. Epub 2022 Apr 12.

RefSeq genomic sequence
See the genomic reference sequence for the PNKP gene (NG_027717.1).
RefSeq protein
See the reference protein sequence for bifunctional polynucleotide phosphatase/kinase (NP_009185.2).

Nucleotide
Nucleotide sequence from coding region
PubMed
PubMed articles cited by protein sequence record
Taxonomy
Taxonomy sequences associated with protein record
BioSystems
BioSystems
CDD Search Results
Display conserved domains within a protein
Conserved Domains (Concise)
Link to a concise list of conserved domains in a protein
Conserved Domains (Full)
Link to conserved domains within a protein
Domain Relatives
Display proteins with similar conserved domain architecture
Gene
Link to related Genes
Identical Structures
3D structures for identical protein sequences
OMIM
OMIM records associated with protein sequence
PubMed (Weighted)
Links to pubmed
Related Structures (List)
List of related structures
Related Structures (Summary)
Related structures

MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF) [MODBASE, Database of Comparat...]
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF)
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome

polynucleotide kinase-3'-phosphatase [Homo sapiens]
polynucleotide kinase-3'-phosphatase [Homo sapiens]
gi|14211141|gb|AAK57340.1|AF354258_

Protein
AGENCOURT_15224198 NICHD_XGC_Swb1 Xenopus tropicalis cDNA clone IMAGE:7000209 5'...
AGENCOURT_15224198 NICHD_XGC_Swb1 Xenopus tropicalis cDNA clone IMAGE:7000209 5', mRNA sequence
gi|33780418|gnl|dbEST|19586148|gb|C 78.1|

Nucleotide
BP706306 Osada Taira anterior neuroectoderm (ANE) pCS105 cDNA library Xenopus la...
BP706306 Osada Taira anterior neuroectoderm (ANE) pCS105 cDNA library Xenopus laevis cDNA clone XL517g22ex 5', mRNA sequence
gi|46054705|gnl|dbEST|24572039|dbj| 306.1|

Nucleotide
SLC22A6 solute carrier family 22 member 6 [Homo sapiens]
SLC22A6 solute carrier family 22 member 6 [Homo sapiens]
Gene ID:9356

Gene
9356[uid] AND (alive[prop]) (1)
Gene

Your browsing activity is empty.

Activity recording is turned off.

Protein