U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    CH1 Pheophorbide a oxygenase family protein with Rieske 2Fe-2S domain-containing protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 841029, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    CH1
    Official Full Name
    Pheophorbide a oxygenase family protein with Rieske 2Fe-2S domain-containing protein
    Primary source
    TAIR:AT1G44446
    Locus tag
    AT1G44446
    See related
    Araport:AT1G44446
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS THALIANA CHLOROPHYLL A OXYGENASE; ATCAO; CAO; CHLORINA 1; CHLOROPHYLL A OXYGENASE; CHLOROPHYLL B SYNTHASE; T18F15.7; T18F15_7
    Summary
    Encodes chlorophyllide <i>a</i> oxygenase which converts chlorophyllide <i>a</i> to chlorophyllide <i>b</i> by catalyzing two successive hydroxylations at the 7-methyl group of chlorophyllide <i>a</i> . Mutants are deficient in pigments that associate with thylakoid membrane proteins, lacking chlorophyll <i>b</i> and light-harvesting proteins of photosystem II. The protein was shown through cross-linking experiments to interact with Toc75, Toc34, Tic40, Tic20 and Tic22.
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See CH1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    8
    Sequence:
    Chromosome: 1; NC_003070.9 (16848308..16851271, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene IAA-amino acid hydrolase ILR1-like 6 Neighboring gene miscRNA Neighboring gene zinc-ribbon domain protein Neighboring gene Cyclophilin Neighboring gene pseudo

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Compensation Mechanism of the Photosynthetic Apparatus in Arabidopsis thaliana ch1 Mutants. Wójtowicz J, et al. Int J Mol Sci, 2020 Dec 28. PMID 33379339, Free PMC Article
    2. Light-induced acclimation of the Arabidopsis chlorina1 mutant to singlet oxygen. Ramel F, et al. Plant Cell, 2013 Apr. PMID 23590883, Free PMC Article
    3. Determination of a chloroplast degron in the regulatory domain of chlorophyllide a oxygenase. Sakuraba Y, et al. J Biol Chem, 2009 Dec 25. PMID 19843523, Free PMC Article
    4. Loss of the N-terminal domain of chlorophyllide a oxygenase induces photodamage during greening of Arabidopsis seedlings. Yamasato A, et al. BMC Plant Biol, 2008 Jun 12. PMID 18549471, Free PMC Article
    5. The N-terminal domain of chlorophyllide a oxygenase confers protein instability in response to chlorophyll B accumulation in Arabidopsis. Yamasato A, et al. Plant Cell, 2005 May. PMID 15805480, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Compensation Mechanism of the Photosynthetic Apparatus in Arabidopsis thaliana ch1 Mutants.
      Title: Compensation Mechanism of the Photosynthetic Apparatus in Arabidopsis thaliana ch1 Mutants.
    2. Data indicate that jasmonate biosynthesis was strongly induced in CH1 (At1g44446) mutant plants under high-light stress.
      Title: Light-induced acclimation of the Arabidopsis chlorina1 mutant to singlet oxygen.
    3. Determination of a chloroplast degron in the regulatory domain of chlorophyllide a oxygenase.
      Title: Determination of a chloroplast degron in the regulatory domain of chlorophyllide a oxygenase.
    4. Data show that the A domain of CAO is essential in the control of chlorophyll biosynthesis and in the survival of seedlings during de-etiolation especially under strong illumination.
      Title: Loss of the N-terminal domain of chlorophyllide a oxygenase induces photodamage during greening of Arabidopsis seedlings.
    5. CAO is involved in the regulated import and stabilization of the chlorophyllide b-binding light-harvesting proteins Lhcb1 (LHCII) and Lhcb4 (CP29) in chloroplasts.
      Title: A role for chlorophyllide a oxygenase in the regulated import and stabilization of light-harvesting chlorophyll a/b proteins.
    6. The mechanism which regulates Chl a/b ratios and whether the changes in Chl a/b ratios are essential in regulation of LHC accumulation during light acclimation was studied.
      Title: Effects of chlorophyllide a oxygenase overexpression on light acclimation in Arabidopsis thaliana.
    Submit: New GeneRIF Correction

    Pathways from PubChem

    Go to the top of the page

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    NM_001333230.1
    NM_103548.5
    NM_202240.2
    NM_202241.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables chlorophyllide a oxygenase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables chlorophyllide a oxygenase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables chlorophyllide a oxygenase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables iron ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in chlorophyll biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within chlorophyll biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in chloroplast ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    located_in chloroplast inner membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in thylakoid membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    Pheophorbide a oxygenase family protein with Rieske 2Fe-2S domain-containing protein
    NP_175088.1
    • CHLORINA 1 (CH1); CONTAINS InterPro DOMAIN/s: Rieske [2Fe-2S] iron-sulphur domain (InterPro:IPR017941), Aromatic-ring-hydroxylating dioxygenase, 2Fe-2S-binding site (InterPro:IPR015881), Pheophorbide a oxygenase (InterPro:IPR013626); BEST Arabidopsis thaliana protein match is: translocon at the inner envelope membrane of chloroplasts 55-II (TAIR:AT2G24820.1); Has 6355 Blast hits to 6353 proteins in 945 species: Archae - 23; Bacteria - 4238; Metazoa - 95; Fungi - 51; Plants - 426; Viruses - 0; Other Eukaryotes - 1522 (source: NCBI BLink).
    NP_973969.1
    • CHLORINA 1 (CH1); CONTAINS InterPro DOMAIN/s: Aromatic-ring-hydroxylating dioxygenase, 2Fe-2S-binding site (InterPro:IPR015881), Rieske [2Fe-2S] iron-sulphur domain (InterPro:IPR017941), Pheophorbide a oxygenase (InterPro:IPR013626); BEST Arabidopsis thaliana protein match is: translocon at the inner envelope membrane of chloroplasts 55-II (TAIR:AT2G24820.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
    NP_973970.1
    • CHLORINA 1 (CH1); CONTAINS InterPro DOMAIN/s: Aromatic-ring-hydroxylating dioxygenase, 2Fe-2S-binding site (InterPro:IPR015881), Rieske [2Fe-2S] iron-sulphur domain (InterPro:IPR017941); BEST Arabidopsis thaliana protein match is: translocon at the inner envelope membrane of chloroplasts 55-II (TAIR:AT2G24820.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      16848308..16851271 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_103548.5 → NP_175088.1  Pheophorbide a oxygenase family protein with Rieske 2Fe-2S domain-containing protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_175088.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q0WQP6, Q3ECX2, Q3ECX3, Q9MBA1, Q9SPF2, Q9XJ37
      UniProtKB/TrEMBL
      A0A178W6L1, A0A5S9WPC9
      Conserved Domains (1) summary
      PLN02281
      Location:1 → 536
      PLN02281; chlorophyllide a oxygenase

    2. NM_202241.2 → NP_973970.1  Pheophorbide a oxygenase family protein with Rieske 2Fe-2S domain-containing protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_973970.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9MBA1
      Conserved Domains (2) summary
      PLN02281
      Location:1 → 386
      PLN02281; chlorophyllide a oxygenase
      cd04337
      Location:204 → 332
      Rieske_RO_Alpha_Cao; Cao (chlorophyll a oxygenase) is a rieske non-heme iron-sulfur protein located within the plastid-envelope inner and thylakoid membranes, that catalyzes the conversion of chlorophyllide a to chlorophyllide b. CAO is found not only in plants but also in ...

    3. NM_001333230.1 → NP_001321683.1  Pheophorbide a oxygenase family protein with Rieske 2Fe-2S domain-containing protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8ARR2

    4. NM_202240.2 → NP_973969.1  Pheophorbide a oxygenase family protein with Rieske 2Fe-2S domain-containing protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_973969.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9MBA1
      Conserved Domains (3) summary
      PLN02281
      Location:1 → 511
      PLN02281; chlorophyllide a oxygenase
      cd04337
      Location:204 → 332
      Rieske_RO_Alpha_Cao; Cao (chlorophyll a oxygenase) is a rieske non-heme iron-sulfur protein located within the plastid-envelope inner and thylakoid membranes, that catalyzes the conversion of chlorophyllide a to chlorophyllide b. CAO is found not only in plants but also in ...
      pfam08417
      Location:408 → 480
      PaO; Pheophorbide a oxygenase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9MBA1.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools