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    PTB3 polypyrimidine tract-binding protein 3 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 840918, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PTB3
    Official Full Name
    polypyrimidine tract-binding protein 3
    Primary source
    TAIR:AT1G43190
    Locus tag
    AT1G43190
    See related
    Araport:AT1G43190
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F1I21.14; F1I21_14; polypyrimidine tract-binding protein 3
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    Genomic context

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    See PTB3 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    15
    Sequence:
    Chromosome: 1; NC_003070.9 (16275108..16278742, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene B3 domain protein Neighboring gene miscRNA Neighboring gene pseudo Neighboring gene pseudo

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Polypyrimidine tract-binding protein homologues from Arabidopsis underlie regulatory circuits based on alternative splicing and downstream control. Stauffer E, et al. Plant J, 2010 Oct. PMID 20735772
    2. Protein and metabolite composition of Arabidopsis stress granules. Kosmacz M, et al. New Phytol, 2019 May. PMID 30664249
    3. In Planta Determination of the mRNA-Binding Proteome of Arabidopsis Etiolated Seedlings. Reichel M, et al. Plant Cell, 2016 Oct. PMID 27729395, Free PMC Article
    4. Discovering the RNA-Binding Proteome of Plant Leaves with an Improved RNA Interactome Capture Method. Bach-Pages M, et al. Biomolecules, 2020 Apr 24. PMID 32344669, Free PMC Article
    5. Advanced proteomic analyses yield a deep catalog of ubiquitylation targets in Arabidopsis. Kim DY, et al. Plant Cell, 2013 May. PMID 23667124, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001084203.1
    NM_001084204.1
    NM_103470.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables mRNA binding HDA PubMed 
    enables mRNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within regulation of RNA splicing IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of translation IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in P-body IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasmic stress granule IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    polypyrimidine tract-binding protein 3
    NP_001077672.1
    • polypyrimidine tract-binding protein 3 (PTB3); FUNCTIONS IN: RNA binding, nucleotide binding, nucleic acid binding; INVOLVED IN: regulation of RNA splicing, regulation of translation; LOCATED IN: nucleus, cytoplasmic mRNA processing body, cytoplasm; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: RNA recognition motif, RNP-1 (InterPro:IPR000504), HnRNP-L/PTB/hephaestus splicing factor (InterPro:IPR006536), Nucleotide-binding, alpha-beta plait (InterPro:IPR012677); BEST Arabidopsis thaliana protein match is: polypyrimidine tract-binding protein 1 (TAIR:AT3G01150.1); Has 2350 Blast hits to 1929 proteins in 173 species: Archae - 0; Bacteria - 0; Metazoa - 1455; Fungi - 41; Plants - 581; Viruses - 0; Other Eukaryotes - 273 (source: NCBI BLink).
    NP_001077673.1
    • polypyrimidine tract-binding protein 3 (PTB3); FUNCTIONS IN: RNA binding, nucleotide binding, nucleic acid binding; INVOLVED IN: regulation of RNA splicing, regulation of translation; LOCATED IN: nucleus, cytoplasmic mRNA processing body, cytoplasm; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: RNA recognition motif, RNP-1 (InterPro:IPR000504), HnRNP-L/PTB/hephaestus splicing factor (InterPro:IPR006536), Nucleotide-binding, alpha-beta plait (InterPro:IPR012677); BEST Arabidopsis thaliana protein match is: polypyrimidine tract-binding protein 1 (TAIR:AT3G01150.1); Has 2368 Blast hits to 1946 proteins in 170 species: Archae - 0; Bacteria - 0; Metazoa - 1467; Fungi - 40; Plants - 582; Viruses - 0; Other Eukaryotes - 279 (source: NCBI BLink).
    NP_175010.2
    • polypyrimidine tract-binding protein 3 (PTB3); FUNCTIONS IN: RNA binding, nucleotide binding, nucleic acid binding; INVOLVED IN: regulation of RNA splicing, regulation of translation; LOCATED IN: nucleus, cytoplasmic mRNA processing body, cytoplasm; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: RNA recognition motif, RNP-1 (InterPro:IPR000504), HnRNP-L/PTB/hephaestus splicing factor (InterPro:IPR006536), Nucleotide-binding, alpha-beta plait (InterPro:IPR012677); BEST Arabidopsis thaliana protein match is: polypyrimidine tract-binding protein 1 (TAIR:AT3G01150.1); Has 2350 Blast hits to 1929 proteins in 173 species: Archae - 0; Bacteria - 0; Metazoa - 1455; Fungi - 41; Plants - 581; Viruses - 0; Other Eukaryotes - 273 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      16275108..16278742 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_103470.5 → NP_175010.2  polypyrimidine tract-binding protein 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_175010.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q6ICX4
      UniProtKB/TrEMBL
      A0A5S9WMB4, A0A654EFU1, Q0WQH0
      Conserved Domains (5) summary
      cd12426
      Location:348 → 426
      RRM4_PTBPH3; RNA recognition motif 4 in plant polypyrimidine tract-binding protein homolog 3 (PTBPH3)
      cd12687
      Location:6 → 80
      RRM1_PTBPH3; RNA recognition motif 1 in plant polypyrimidine tract-binding protein homolog 3 (PTBPH3)
      cd12692
      Location:97 → 184
      RRM2_PTBPH3; RNA recognition motif 2 in plant polypyrimidine tract-binding protein homolog 3 (PTBPH3)
      cd12698
      Location:244 → 319
      RRM3_PTBPH3; RNA recognition motif 3 in plant polypyrimidine tract-binding protein homolog 3 (PTBPH3)
      TIGR01649
      Location:5 → 427
      hnRNP-L_PTB; hnRNP-L/PTB/hephaestus splicing factor family

    2. NM_001084204.1 → NP_001077673.1  polypyrimidine tract-binding protein 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001077673.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5S9WMB4, A0A654EFU1, A8MR27
      Conserved Domains (5) summary
      cd12426
      Location:346 → 424
      RRM4_PTBPH3; RNA recognition motif 4 in plant polypyrimidine tract-binding protein homolog 3 (PTBPH3)
      cd12692
      Location:95 → 182
      RRM2_PTBPH3; RNA recognition motif 2 in plant polypyrimidine tract-binding protein homolog 3 (PTBPH3)
      cd12698
      Location:242 → 317
      RRM3_PTBPH3; RNA recognition motif 3 in plant polypyrimidine tract-binding protein homolog 3 (PTBPH3)
      TIGR01649
      Location:5 → 425
      hnRNP-L_PTB; hnRNP-L/PTB/hephaestus splicing factor family
      cl17169
      Location:6 → 78
      RRM_SF; RNA recognition motif (RRM) superfamily

    3. NM_001084203.1 → NP_001077672.1  polypyrimidine tract-binding protein 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001077672.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q6ICX4
      UniProtKB/TrEMBL
      A0A5S9WMB4, A0A654EFU1, Q0WQH0
      Conserved Domains (5) summary
      cd12426
      Location:348 → 426
      RRM4_PTBPH3; RNA recognition motif 4 in plant polypyrimidine tract-binding protein homolog 3 (PTBPH3)
      cd12687
      Location:6 → 80
      RRM1_PTBPH3; RNA recognition motif 1 in plant polypyrimidine tract-binding protein homolog 3 (PTBPH3)
      cd12692
      Location:97 → 184
      RRM2_PTBPH3; RNA recognition motif 2 in plant polypyrimidine tract-binding protein homolog 3 (PTBPH3)
      cd12698
      Location:244 → 319
      RRM3_PTBPH3; RNA recognition motif 3 in plant polypyrimidine tract-binding protein homolog 3 (PTBPH3)
      TIGR01649
      Location:5 → 427
      hnRNP-L_PTB; hnRNP-L/PTB/hephaestus splicing factor family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6ICX4.1

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