U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    TUA4 tubulin alpha-4 chain [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 839405, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    TUA4
    Official Full Name
    tubulin alpha-4 chain
    Primary source
    TAIR:AT1G04820
    Locus tag
    AT1G04820
    See related
    Araport:AT1G04820
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F13M7.19; TOR2; TORTIFOLIA 2; tubulin alpha-4 chain
    Summary
    Encodes an alpha tubulin isoform that is expressed in roots, leaves and flowers.
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See TUA4 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    3
    Sequence:
    Chromosome: 1; NC_003070.9 (1356084..1358547, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene RING/U-box superfamily protein Neighboring gene glycine-rich protein Neighboring gene 26S proteasome regulatory complex, non-ATPase subcomplex, Rpn2/Psmd1 subunit Neighboring gene Ypt/Rab-GAP domain of gyp1p superfamily protein Neighboring gene Tetratricopeptide repeat (TPR)-like superfamily protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Helical growth of the Arabidopsis mutant tortifolia2 does not depend on cell division patterns but involves handed twisting of isolated cells. Buschmann H, et al. Plant Cell, 2009 Jul. PMID 19638477, Free PMC Article
    2. Plant gamma-tubulin interacts with alphabeta-tubulin dimers and forms membrane-associated complexes. Dryková D, et al. Plant Cell, 2003 Feb. PMID 12566585, Free PMC Article
    3. The microtubule plus-end tracking proteins SPR1 and EB1b interact to maintain polar cell elongation and directional organ growth in Arabidopsis. Galva C, et al. Plant Cell, 2014 Nov. PMID 25415978, Free PMC Article
    4. Gravity-induced modifications to development in hypocotyls of Arabidopsis tubulin mutants. Matsumoto S, et al. Plant Physiol, 2010 Feb. PMID 20018592, Free PMC Article
    5. The small genome of Arabidopsis contains at least six expressed alpha-tubulin genes. Kopczak SD, et al. Plant Cell, 1992 May. PMID 1498608, Free PMC Article

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Data found that in alpha-tubulin mutant, microtubule dynamicity is reduced and twisting of mutant organs appears to be a higher-order expression of the helical expansion of individual cells.
      Title: Helical growth of the Arabidopsis mutant tortifolia2 does not depend on cell division patterns but involves handed twisting of isolated cells.
    Submit: New GeneRIF Correction

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    NM_100360.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables mRNA binding HDA PubMed 
    enables structural constituent of cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables structural constituent of cytoskeleton ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cellular response to gravity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in microtubule-based process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within microtubule-based process TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast stroma HDA PubMed 
    located_in cytosol HDA PubMed 
    located_in extracellular region HDA PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plant-type cell wall HDA PubMed 
    located_in plant-type vacuole HDA PubMed 
    located_in plasma membrane HDA PubMed 
    part_of tubulin complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    tubulin alpha-4 chain
    NP_171974.1
    • tubulin alpha-4 chain (TUA4); FUNCTIONS IN: structural constituent of cytoskeleton; INVOLVED IN: response to cadmium ion, microtubule-based process, cellular response to gravity; LOCATED IN: tubulin complex, cytosol, cell wall, plasma membrane, chloroplast; EXPRESSED IN: 29 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Alpha tubulin (InterPro:IPR002452), Tubulin (InterPro:IPR000217), Tubulin/FtsZ, GTPase domain (InterPro:IPR003008), Tubulin/FtsZ, N-terminal (InterPro:IPR019746), Tubulin/FtsZ, C-terminal (InterPro:IPR008280), Tubulin, conserved site (InterPro:IPR017975), Tubulin/FtsZ, 2-layer sandwich domain (InterPro:IPR018316); BEST Arabidopsis thaliana protein match is: tubulin alpha-2 chain (TAIR:AT1G50010.1); Has 22626 Blast hits to 22529 proteins in 4679 species: Archae - 4; Bacteria - 25; Metazoa - 4391; Fungi - 13400; Plants - 1532; Viruses - 0; Other Eukaryotes - 3274 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      1356084..1358547 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_100360.4 → NP_171974.1  tubulin alpha-4 chain [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_171974.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B9DGT7, P29510, Q0WV25
      UniProtKB/TrEMBL
      A0A178W5L2, A0A5S9SKW7, Q944I2
      Conserved Domains (1) summary
      PLN00221
      Location:1 → 450
      PLN00221; tubulin alpha chain; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    B9DGT7.2
    Q0WV25.2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials