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    CHX18 cation/H+ exchanger 18 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 834163, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CHX18
    Official Full Name
    cation/H+ exchanger 18
    Primary source
    TAIR:AT5G41610
    Locus tag
    AT5G41610
    See related
    Araport:AT5G41610
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS THALIANA CATION/H+ EXCHANGER 18; ATCHX18; cation/H+ exchanger 18; MBK23.12; MBK23_12
    Summary
    member of Putative Na+/H+ antiporter family
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    Genomic context

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    See CHX18 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    3
    Sequence:
    Chromosome: 5; NC_003076.8 (16638302..16641933, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene VIRB2-interacting protein 3 Neighboring gene tRNA-Leu Neighboring gene ncRNA Neighboring gene intracellular protein transporter USO1-like protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Transporters involved in pH and K+ homeostasis affect pollen wall formation, male fertility, and embryo development. Padmanaban S, et al. J Exp Bot, 2017 Jun 1. PMID 28338823, Free PMC Article
    2. Plant-specific cation/H+ exchanger 17 and its homologs are endomembrane K+ transporters with roles in protein sorting. Chanroj S, et al. J Biol Chem, 2011 Sep 30. PMID 21795714, Free PMC Article
    3. Border control--a membrane-linked interactome of Arabidopsis. Jones AM, et al. Science, 2014 May 16. PMID 24833385
    4. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001344404.1
    NM_001344405.1
    NM_123525.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables sodium:proton antiporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in proton transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within regulation of pH IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in late endosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cation/H+ exchanger 18
    NP_001318723.1
    • ARABIDOPSIS THALIANA CATION/H+ EXCHANGER 18 (ATCHX18); FUNCTIONS IN: monovalent cation:hydrogen antiporter activity, sodium:hydrogen antiporter activity; INVOLVED IN: cation transport; LOCATED IN: integral to membrane; EXPRESSED IN: 10 plant structures; EXPRESSED DURING: 6 growth stages; CONTAINS InterPro DOMAIN/s: Cation/H+ exchanger (InterPro:IPR006153); BEST Arabidopsis thaliana protein match is: cation/H+ exchanger 17 (TAIR:AT4G23700.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
    NP_198976.3
    • cation/H+ exchanger 18 (CHX18); FUNCTIONS IN: monovalent cation:hydrogen antiporter activity, sodium:hydrogen antiporter activity; INVOLVED IN: cation transport; LOCATED IN: integral to membrane; EXPRESSED IN: 10 plant structures; EXPRESSED DURING: 6 growth stages; CONTAINS InterPro DOMAIN/s: Cation/H+ exchanger (InterPro:IPR006153); BEST Arabidopsis thaliana protein match is: cation/H+ exchanger 17 (TAIR:AT4G23700.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      16638302..16641933 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001344404.1 → NP_001318723.1  cation/H+ exchanger 18 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UMU2, A0A7G2FGT1
      Conserved Domains (1) summary
      PLN03159
      Location:1 → 725
      PLN03159; cation/H(+) antiporter 15; Provisional

    2. NM_123525.4 → NP_198976.3  cation/H+ exchanger 18 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_198976.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q3E7L5, Q58P65, Q9FFR9
      UniProtKB/TrEMBL
      A0A5S9YA78, A0A654G712, A0A7G2FGT1
      Conserved Domains (1) summary
      PLN03159
      Location:3 → 793
      PLN03159; cation/H(+) antiporter 15; Provisional

    3. NM_001344405.1 → NP_001332436.1  cation/H+ exchanger 18 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q3E7L5, Q58P65, Q9FFR9
      UniProtKB/TrEMBL
      A0A5S9YA78, A0A654G712, A0A7G2FGT1
      Conserved Domains (1) summary
      PLN03159
      Location:3 → 793
      PLN03159; cation/H(+) antiporter 15; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9FFR9.1

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