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    PFD5 prefoldin 5 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 832393, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PFD5
    Official Full Name
    prefoldin 5
    Primary source
    TAIR:AT5G23290
    Locus tag
    AT5G23290
    See related
    Araport:AT5G23290
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    MKD15.15; MKD15_15; prefoldin 5
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    Genomic context

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    See PFD5 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    4
    Sequence:
    Chromosome: 5; NC_003076.8 (7846081..7847643)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene sugar transporter 11 Neighboring gene TCP family transcription factor Neighboring gene pyrimidine d Neighboring gene Fe superoxide dismutase 3 Neighboring gene S-isoprenylcysteine O-methyltransferase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Dynamic regulation of cortical microtubule organization through prefoldin-DELLA interaction. Locascio A, et al. Curr Biol, 2013 May 6. PMID 23583555
    2. Prefoldin 6 is required for normal microtubule dynamics and organization in Arabidopsis. Gu Y, et al. Proc Natl Acad Sci U S A, 2008 Nov 18. PMID 19004800, Free PMC Article
    3. Prefoldins 3 and 5 play an essential role in Arabidopsis tolerance to salt stress. Rodríguez-Milla MA, et al. Mol Plant, 2009 May. PMID 19825635
    4. Prefoldins contribute to maintaining the levels of the spliceosome LSM2-8 complex through Hsp90 in Arabidopsis. Esteve-Bruna D, et al. Nucleic Acids Res, 2020 Jun 19. PMID 32396196, Free PMC Article
    5. Prefoldins Negatively Regulate Cold Acclimation in Arabidopsis thaliana by Promoting Nuclear Proteasome-Mediated HY5 Degradation. Perea-Resa C, et al. Mol Plant, 2017 Jun 5. PMID 28412546

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_122235.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables unfolded protein binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cellular response to gibberellin stimulus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_negative_effect cold acclimation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in cortical microtubule organization IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_positive_effect mRNA processing ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in protein folding IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in response to cold IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within response to salt stress IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plastid HDA PubMed 
    part_of prefoldin complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    prefoldin 5
    NP_197720.1
    • prefoldin 5 (PFD5); FUNCTIONS IN: unfolded protein binding; INVOLVED IN: protein folding; LOCATED IN: prefoldin complex; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Prefoldin alpha-like (InterPro:IPR004127), Prefoldin (InterPro:IPR009053), Prefoldin alpha subunit (InterPro:IPR011599); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      7846081..7847643
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_122235.2 → NP_197720.1  prefoldin 5 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_197720.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P57742
      UniProtKB/TrEMBL
      A0A178UJZ9, A0A5S9Y8U5
      Conserved Domains (1) summary
      TIGR00293
      Location:15 → 141
      TIGR00293; prefoldin, archaeal alpha subunit/eukaryotic subunit 5
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P57742.1

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