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    AHBP-1B bZIP transcription factor family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 830586, updated on 18-Sep-2024

    Summary

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    Official Symbol
    AHBP-1B
    Official Full Name
    bZIP transcription factor family protein
    Primary source
    TAIR:AT5G06950
    Locus tag
    AT5G06950
    See related
    Araport:AT5G06950
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtTGA2; MOJ9.12; MOJ9_12; TGA2; TGACG sequence-specific binding protein 2
    Summary
    Transcription factor of the B-ZIP family that has high affinity for C-box motifs. Interacts with NPR1 and may regulate PR gene expression. Phosphorylated by a CK2-like protein in vitro. Phosphorylation is enhanced by salicylic acid treatment.
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    Genomic context

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    See AHBP-1B in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    11
    Sequence:
    Chromosome: 5; NC_003076.8 (2150840..2154586)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene FASCICLIN-like arabinogalactan protein 21 precursor Neighboring gene nucleolar-like protein Neighboring gene Leucine-rich repeat receptor-like protein kinase family protein Neighboring gene OCS-element binding factor 5 Neighboring gene plant/protein (DUF810)

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The TGA Transcription Factors from Clade II Negatively Regulate the Salicylic Acid Accumulation in Arabidopsis. Fonseca A, et al. Int J Mol Sci, 2022 Oct 1. PMID 36232932, Free PMC Article
    2. Salicylic acid-inducible Arabidopsis CK2-like activity phosphorylates TGA2. Kang HG, et al. Plant Mol Biol, 2005 Mar. PMID 15821979
    3. Direct visualization of protein interactions in plant cells. Subramaniam R, et al. Nat Biotechnol, 2001 Aug. PMID 11479572
    4. Binding specificity and tissue-specific expression pattern of the Arabidopsis bZIP transcription factor TGA2. de Pater S, et al. Mol Gen Genet, 1996 Feb 5. PMID 8628224
    5. TGACG-BINDING FACTOR 1 (TGA1) and TGA4 regulate salicylic acid and pipecolic acid biosynthesis by modulating the expression of SYSTEMIC ACQUIRED RESISTANCE DEFICIENT 1 (SARD1) and CALMODULIN-BINDING PROTEIN 60g (CBP60g). Sun T, et al. New Phytol, 2018 Jan. PMID 28898429

    See all (44) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Our study showed that TGA1 and TGA4 regulate Pip and SA biosynthesis by modulating the expression of SARD1 and CBP60g.
      Title: TGACG-BINDING FACTOR 1 (TGA1) and TGA4 regulate salicylic acid and pipecolic acid biosynthesis by modulating the expression of SYSTEMIC ACQUIRED RESISTANCE DEFICIENT 1 (SARD1) and CALMODULIN-BINDING PROTEIN 60g (CBP60g).
    2. AtNPR1, AtGA2, and AtPR-5, encoding specific components involved in salicylic acid regulation, synthesis, and signaling, are overexpressed in soybean roots, resistance to soybean cyst nematode is enhanced.
      Title: Arabidopsis genes, AtNPR1, AtTGA2 and AtPR-5, confer partial resistance to soybean cyst nematode (Heterodera glycines) when overexpressed in transgenic soybean roots.
    3. TGA factors 2, 5, and 6 activate oxylipin-responsive gene expression but impede inhibition of root growth by oxylipins.
      Title: TGA transcription factors and jasmonate-independent COI1 signalling regulate specific plant responses to reactive oxylipins.
    4. TGA2-binding motif is directly involved in the modulation of salicylic acid-induced NIMIN-1 expression in Arabidopsis.
      Title: Functional analysis of a TGA factor-binding site located in the promoter region controlling salicylic acid-induced NIMIN-1 expression in Arabidopsis.
    5. data show TGA factors, which are essential for the salicylic acid (SA)-dependent establishment of systemic acquired resistance, play a pivotal role in the activation of the jasmonic acid/ethylene pathway, both after pathogen infection & hormone treatment
      Title: Arabidopsis thaliana class-II TGA transcription factors are essential activators of jasmonic acid/ethylene-induced defense responses.
    6. We confirm that the NPR1 BTB/POZ domain interacts with and negates the molecular function of the TGA2 repression domain by excluding TGA2 oligomers from cognate DNA.
      Title: The BTB/POZ domain of the Arabidopsis disease resistance protein NPR1 interacts with the repression domain of TGA2 to negate its function.
    7. NPR1 may transiently interact with the DNA unbound fraction of TGA2 to promote its recruitment to an active form on cognate target promoters.
      Title: NPR1 preferentially binds to the DNA-inactive form of Arabidopsis TGA2.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001036768.2
    NM_001085070.2
    NM_001342913.1
    NM_120777.3
    NM_203015.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables transcription cis-regulatory region binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within negative regulation of DNA-templated transcription IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within positive regulation of DNA-templated transcription IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within response to xenobiotic stimulus IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_negative_effect salicylic acid biosynthetic process IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within systemic acquired resistance, salicylic acid mediated signaling pathway TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    bZIP transcription factor family protein
    NP_001031845.1
    • AHBP-1B; CONTAINS InterPro DOMAIN/s: Basic-leucine zipper (bZIP) transcription factor (InterPro:IPR004827), bZIP transcription factor, bZIP-1 (InterPro:IPR011616); BEST Arabidopsis thaliana protein match is: TGACG motif-binding factor 6 (TAIR:AT3G12250.2); Has 882 Blast hits to 882 proteins in 71 species: Archae - 0; Bacteria - 9; Metazoa - 3; Fungi - 6; Plants - 812; Viruses - 0; Other Eukaryotes - 52 (source: NCBI BLink).
    NP_001078539.1
    • AHBP-1B; CONTAINS InterPro DOMAIN/s: Basic-leucine zipper (bZIP) transcription factor (InterPro:IPR004827), bZIP transcription factor, bZIP-1 (InterPro:IPR011616); BEST Arabidopsis thaliana protein match is: TGACG motif-binding factor 6 (TAIR:AT3G12250.2); Has 882 Blast hits to 882 proteins in 71 species: Archae - 0; Bacteria - 9; Metazoa - 3; Fungi - 6; Plants - 812; Viruses - 0; Other Eukaryotes - 52 (source: NCBI BLink).
    NP_196312.1
    • AHBP-1B; CONTAINS InterPro DOMAIN/s: Basic-leucine zipper (bZIP) transcription factor (InterPro:IPR004827), bZIP transcription factor, bZIP-1 (InterPro:IPR011616); BEST Arabidopsis thaliana protein match is: TGACG motif-binding factor 6 (TAIR:AT3G12250.2); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).
    NP_974744.1
    • AHBP-1B; CONTAINS InterPro DOMAIN/s: Basic-leucine zipper (bZIP) transcription factor (InterPro:IPR004827), bZIP transcription factor, bZIP-1 (InterPro:IPR011616); BEST Arabidopsis thaliana protein match is: TGACG motif-binding factor 6 (TAIR:AT3G12250.2); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      2150840..2154586
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_120777.3 → NP_196312.1  bZIP transcription factor family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_196312.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P43273
      UniProtKB/TrEMBL
      A0A178UBE9, A0A384LQJ8, B2BDR5, B2BDS4
      Conserved Domains (3) summary
      cd14686
      Location:47 → 98
      bZIP; coiled coil [structural motif]
      pfam14144
      Location:128 → 203
      DOG1; Seed dormancy control
      cl21462
      Location:46 → 98
      bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain

    2. NM_001085070.2 → NP_001078539.1  bZIP transcription factor family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001078539.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P43273
      UniProtKB/TrEMBL
      A0A178UBE9, A0A384LQJ8, B2BDR5, B2BDS4
      Conserved Domains (3) summary
      cd14686
      Location:47 → 98
      bZIP; coiled coil [structural motif]
      pfam14144
      Location:128 → 203
      DOG1; Seed dormancy control
      cl21462
      Location:46 → 98
      bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain

    3. NM_001036768.2 → NP_001031845.1  bZIP transcription factor family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001031845.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P43273
      UniProtKB/TrEMBL
      A0A178UBE9, A0A384LQJ8, B2BDR5, B2BDS4
      Conserved Domains (3) summary
      cd14686
      Location:47 → 98
      bZIP; coiled coil [structural motif]
      pfam14144
      Location:128 → 203
      DOG1; Seed dormancy control
      cl21462
      Location:46 → 98
      bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain

    4. NM_203015.1 → NP_974744.1  bZIP transcription factor family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_974744.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P43273
      UniProtKB/TrEMBL
      A0A178UBE9, A0A384LQJ8, B2BDR5, B2BDS4
      Conserved Domains (3) summary
      cd14686
      Location:47 → 98
      bZIP; coiled coil [structural motif]
      pfam14144
      Location:128 → 203
      DOG1; Seed dormancy control
      cl21462
      Location:46 → 98
      bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain

    5. NM_001342913.1 → NP_001331392.1  bZIP transcription factor family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P43273
      UniProtKB/TrEMBL
      A0A178UBE9, A0A384LQJ8, B2BDR5, B2BDS4
      Conserved Domains (3) summary
      cd14686
      Location:47 → 98
      bZIP; coiled coil [structural motif]
      pfam14144
      Location:128 → 203
      DOG1; Seed dormancy control
      cl21462
      Location:46 → 98
      bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P43273.1

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