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    SK12 SKP1-like 12 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 829598, updated on 18-Sep-2024

    Summary

    Official Symbol
    SK12
    Official Full Name
    SKP1-like 12
    Primary source
    TAIR:AT4G34470
    Locus tag
    AT4G34470
    See related
    Araport:AT4G34470
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ASK12; SKP1-like 12; T4L20.50; T4L20_50
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    Genomic context

    See SK12 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    1
    Sequence:
    Chromosome: 4; NC_003075.7 (16480008..16480616, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene coatomer gamma-2 subunit, putative / gamma-2 coat protein, putative / gamma-2 COP Neighboring gene GTP binding protein beta 1 Neighboring gene O-Glycosyl hydrolases family 17 protein Neighboring gene cyclase associated protein 1

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within ubiquitin-dependent protein catabolic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 

    General protein information

    Preferred Names
    SKP1-like 12
    NP_567967.1
    • SKP1-like 12 (SK12); FUNCTIONS IN: ubiquitin-protein ligase activity, protein binding; INVOLVED IN: ubiquitin-dependent protein catabolic process; LOCATED IN: endomembrane system; EXPRESSED IN: inflorescence; EXPRESSED DURING: seedling growth; CONTAINS InterPro DOMAIN/s: E3 ubiquitin ligase, SCF complex, Skp subunit (InterPro:IPR016897), SKP1 component, dimerisation (InterPro:IPR016072), SKP1 component (InterPro:IPR001232), BTB/POZ fold (InterPro:IPR011333), SKP1 component, POZ (InterPro:IPR016073); BEST Arabidopsis thaliana protein match is: SKP1-like 11 (TAIR:AT4G34210.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      16480008..16480616 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_119612.2NP_567967.1  SKP1-like 12 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_567967.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O65674
      UniProtKB/TrEMBL
      A0A178V344, A0A5S9XZD0
      Conserved Domains (3) summary
      smart00512
      Location:3102
      Skp1; Found in Skp1 protein family
      COG5201
      Location:5150
      SKP1; SCF ubiquitin ligase, SKP1 component [Posttranslational modification, protein turnover, chaperones]
      pfam01466
      Location:77150
      Skp1; Skp1 family, dimerization domain