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    ROPGEF6 ROP (rho of plants) guanine nucleotide exchange factor 6 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 824732, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ROPGEF6
    Official Full Name
    ROP (rho of plants) guanine nucleotide exchange factor 6
    Primary source
    TAIR:AT3G55660
    Locus tag
    AT3G55660
    See related
    Araport:AT3G55660
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATROPGEF6; KINASE PARTNER PROTEIN-LIKE; KPP-LIKE; ROP (rho of plants) guanine nucleotide exchange factor 6
    Summary
    Encodes a member of KPP-like gene family, homolog of KPP (kinase partner protein) gene in tomato. Also a member of the RopGEF (guanine nucleotide exchange factor) family, containing the novel PRONE domain (plant-specific Rop nucleotide exchanger), which is exclusively active towards members of the Rop subfamily.
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    Genomic context

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    See ROPGEF6 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    6
    Sequence:
    Chromosome: 3; NC_003074.8 (20648794..20651484, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene TPRXL Neighboring gene Pyruvate kinase family protein Neighboring gene Plant self-incompatibility protein S1 family Neighboring gene ncRNA Neighboring gene F-box/FBD/LRR protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new family of RhoGEFs activates the Rop molecular switch in plants. Berken A, et al. Nature, 2005 Aug 25. PMID 15980860
    2. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713
    3. Multi-omics network-based functional annotation of unknown Arabidopsis genes. Depuydt T, et al. Plant J, 2021 Nov. PMID 34562334

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    NM_115424.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables guanyl-nucleotide exchange factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    ROP (rho of plants) guanine nucleotide exchange factor 6
    NP_191125.1
    • ROP (rho of plants) guanine nucleotide exchange factor 6 (ROPGEF6); FUNCTIONS IN: Rho guanyl-nucleotide exchange factor activity; INVOLVED IN: biological_process unknown; LOCATED IN: chloroplast; EXPRESSED IN: 16 plant structures; EXPRESSED DURING: 9 growth stages; CONTAINS InterPro DOMAIN/s: Rop nucleotide exchanger, PRONE (InterPro:IPR005512); BEST Arabidopsis thaliana protein match is: ROP guanine nucleotide exchange factor 5 (TAIR:AT5G05940.1); Has 306 Blast hits to 304 proteins in 17 species: Archae - 0; Bacteria - 2; Metazoa - 0; Fungi - 0; Plants - 304; Viruses - 0; Other Eukaryotes - 0 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      20648794..20651484 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001339743.1 → NP_001325478.1  ROP (rho of plants) guanine nucleotide exchange factor 6 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1I9LLC8

    2. NM_115424.3 → NP_191125.1  ROP (rho of plants) guanine nucleotide exchange factor 6 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_191125.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9M056
      UniProtKB/TrEMBL
      A0A7G2EUD2
      Conserved Domains (1) summary
      pfam03759
      Location:106 → 468
      PRONE; PRONE (Plant-specific Rop nucleotide exchanger)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9M056.1

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