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    UVH3 5'-3' exonuclease family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 822427, updated on 18-Sep-2024

    Summary

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    Official Symbol
    UVH3
    Official Full Name
    5'-3' exonuclease family protein
    Primary source
    TAIR:AT3G28030
    Locus tag
    AT3G28030
    See related
    Araport:AT3G28030
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ULTRAVIOLET HYPERSENSITIVE 3; UV REPAIR DEFECTIVE 1; UVR1
    Summary
    Required for repair of pyrimidine-pyrimidinone (6-4) dimers.
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    Genomic context

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    See UVH3 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    18
    Sequence:
    Chromosome: 3; NC_003074.8 (10424179..10431364)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene DNA-binding protein Neighboring gene Leucine-rich receptor-like protein kinase family protein Neighboring gene nodulin MtN21 /EamA-like transporter family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Ultraviolet B radiation enhances a phytochrome-B-mediated photomorphogenic response in Arabidopsis. Boccalandro HE, et al. Plant Physiol, 2001 Jun. PMID 11402206, Free PMC Article
    2. UV- and gamma-radiation sensitive mutants of Arabidopsis thaliana. Jiang CZ, et al. Genetics, 1997 Nov. PMID 9383080, Free PMC Article
    3. Heat stress phenotypes of Arabidopsis mutants implicate multiple signaling pathways in the acquisition of thermotolerance. Larkindale J, et al. Plant Physiol, 2005 Jun. PMID 15923322, Free PMC Article
    4. Proteomic profiling of tandem affinity purified 14-3-3 protein complexes in Arabidopsis thaliana. Chang IF, et al. Proteomics, 2009 Jun. PMID 19452453, Free PMC Article
    5. Identification of ubiquitinated proteins in Arabidopsis. Manzano C, et al. Plant Mol Biol, 2008 Sep. PMID 18535787

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001338928.1
    NM_001338929.1
    NM_001338930.1
    NM_001338931.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables endonuclease activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables single-stranded DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within non-photoreactive DNA repair IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in nucleotide-excision repair IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within response to UV-B IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within response to heat IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    5'-3' exonuclease family protein
    NP_001319661.1
    • ULTRAVIOLET HYPERSENSITIVE 3 (UVH3); FUNCTIONS IN: protein binding, nuclease activity; INVOLVED IN: DNA repair, response to UV-B, response to heat, non-photoreactive DNA repair; LOCATED IN: nucleus; EXPRESSED IN: stem, leaf whorl, seed; EXPRESSED DURING: E expanded cotyledon stage; CONTAINS InterPro DOMAIN/s: XPG conserved site (InterPro:IPR019974), Xeroderma pigmentosum group G protein (InterPro:IPR001044), XPG N-terminal (InterPro:IPR006085), DNA repair protein (XPGC)/yeast Rad (InterPro:IPR006084), 5'-3' exonuclease, C-terminal subdomain (InterPro:IPR020045), Helix-hairpin-helix motif, class 2 (InterPro:IPR008918), XPG/RAD2 endonuclease (InterPro:IPR006086); BEST Arabidopsis thaliana protein match is: 5'-3' exonuclease family protein (TAIR:AT1G01880.1); Has 8115 Blast hits to 5779 proteins in 624 species: Archae - 528; Bacteria - 414; Metazoa - 2441; Fungi - 1496; Plants - 576; Viruses - 71; Other Eukaryotes - 2589 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      10424179..10431364
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001338928.1 → NP_001319661.1  5'-3' exonuclease family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9ATY5, Q9LRT2
      UniProtKB/TrEMBL
      A0A2H1ZEJ7

    2. NM_001338929.1 → NP_001325749.1  5'-3' exonuclease family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VB00, A0A1I9LM67

    3. NM_001338930.1 → NP_001325748.1  5'-3' exonuclease family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9ATY5, Q9LRT2
      UniProtKB/TrEMBL
      A0A1I9LM66

    4. NM_001338931.1 → NP_001325750.1  5'-3' exonuclease family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1I9LM68
    Nucleotide Protein
    Heading Accession and Version

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