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    IREG1 iron regulated 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 818427, updated on 18-Sep-2024

    Summary

    Official Symbol
    IREG1
    Official Full Name
    iron regulated 1
    Primary source
    TAIR:AT2G38460
    Locus tag
    AT2G38460
    See related
    Araport:AT2G38460
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS THALIANA IRON-REGULATED PROTEIN 1; ATIREG1; FERROPORTIN 1; FPN1; iron regulated 1; T19C21.5; T19C21_5
    Summary
    Encodes IRON REGULATED1 (IREG1/FPN1), one of the Arabidopsis orthologs (AT2G38460/IREG1/FPN1 and AT5G03570/IREG2/FPN2) the iron efflux transporter ferroportin (FPN) identified in animals.
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    Genomic context

    See IREG1 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    7
    Sequence:
    Chromosome: 2; NC_003071.7 (16103164..16106208)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene SCAR homolog 2 Neighboring gene Sel1 repeat protein Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene WRKY DNA-binding protein 33

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    NM_001336702.1
    NM_001336703.1
    NM_001336704.1
    NM_001336705.1
    NM_129402.6

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables iron ion transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within cobalt ion transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in iron ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
     

    General protein information

    Preferred Names
    iron regulated 1
    NP_181380.1
    • iron regulated 1 (IREG1); CONTAINS InterPro DOMAIN/s: Ferroporti-1 (InterPro:IPR009716), Major facilitator superfamily, general substrate transporter (InterPro:IPR016196); BEST Arabidopsis thaliana protein match is: iron regulated 2 (TAIR:AT5G03570.2); Has 345 Blast hits to 287 proteins in 82 species: Archae - 0; Bacteria - 2; Metazoa - 164; Fungi - 61; Plants - 95; Viruses - 0; Other Eukaryotes - 23 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      16103164..16106208
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001336699.1NP_001323536.1  iron regulated 1 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8AXC7
    2. NM_001336700.1NP_001323537.1  iron regulated 1 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O80905
      UniProtKB/TrEMBL
      A0A5S9X567, A0A654F014
      Conserved Domains (1) summary
      pfam06963
      Location:35483
      FPN1; Ferroportin1 (FPN1)
    3. NM_001336701.1NP_001323539.1  iron regulated 1 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O80905
      UniProtKB/TrEMBL
      A0A5S9X567, A0A654F014
      Conserved Domains (1) summary
      pfam06963
      Location:35483
      FPN1; Ferroportin1 (FPN1)
    4. NM_129402.6NP_181380.1  iron regulated 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_181380.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O80905
      UniProtKB/TrEMBL
      A0A5S9X567, A0A654F014
      Conserved Domains (1) summary
      pfam06963
      Location:35483
      FPN1; Ferroportin1 (FPN1)
    5. NM_001336702.1NP_001323540.1  iron regulated 1 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8AXC7
    6. NM_001336703.1NP_001323535.1  iron regulated 1 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O80905
      UniProtKB/TrEMBL
      A0A5S9X567, A0A654F014
      Conserved Domains (1) summary
      pfam06963
      Location:35483
      FPN1; Ferroportin1 (FPN1)
    7. NM_001336704.1NP_001323538.1  iron regulated 1 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O80905
      UniProtKB/TrEMBL
      A0A5S9X567, A0A654F014
      Conserved Domains (1) summary
      pfam06963
      Location:35483
      FPN1; Ferroportin1 (FPN1)
    8. NM_001336705.1NP_001323541.1  iron regulated 1 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O80905
      UniProtKB/TrEMBL
      A0A5S9X567, A0A654F014
      Conserved Domains (1) summary
      pfam06963
      Location:35483
      FPN1; Ferroportin1 (FPN1)