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    SK3 SKP1-like 3 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 817111, updated on 18-Sep-2024

    Summary

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    Official Symbol
    SK3
    Official Full Name
    SKP1-like 3
    Primary source
    TAIR:AT2G25700
    Locus tag
    AT2G25700
    See related
    Araport:AT2G25700
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ASK3; F3N11.15; F3N11_15; SKP1-like 3
    Summary
    E3 ubiquitin ligase SCF complex subunit SKP1/ASK1 (At3), putative, E3 ubiquitin ligase; similar to fimbriata-associated protein fap1 GI:2673868 from (Antirrhinum majus. Interacts with F-box proteins.
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    Genomic context

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    See SK3 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    2
    Sequence:
    Chromosome: 2; NC_003071.7 (10948747..10949626, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene miscRNA Neighboring gene DUF581 family protein, putative (DUF581) Neighboring gene holocarboxylase synthase 1 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. bHLH transcription factors that facilitate K⁺ uptake during stomatal opening are repressed by abscisic acid through phosphorylation. Takahashi Y, et al. Sci Signal, 2013 Jun 18. PMID 23779086
    2. The SKP1-like gene family of Arabidopsis exhibits a high degree of differential gene expression and gene product interaction during development. Dezfulian MH, et al. PLoS One, 2012. PMID 23226441, Free PMC Article
    3. E3 SUMO ligase AtSIZ1 positively regulates SLY1-mediated GA signalling and plant development. Kim SI, et al. Biochem J, 2015 Jul 15. PMID 26008766
    4. Identification of ASK and clock-associated proteins as molecular partners of LKP2 (LOV kelch protein 2) in Arabidopsis. Yasuhara M, et al. J Exp Bot, 2004 Sep. PMID 15310821
    5. Functional analysis of EID1, an F-box protein involved in phytochrome A-dependent light signal transduction. Marrocco K, et al. Plant J, 2006 Feb. PMID 16412087

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. ABA induced the phosphorylation of three basic helix-loop-helix (bHLH) transcription factors, called AKSs (ABA-responsive kinase substrates; AKS1, AKS2, and AKS3), in Arabidopsis guard cells
      Title: bHLH transcription factors that facilitate K⁺ uptake during stomatal opening are repressed by abscisic acid through phosphorylation.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_128129.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    SKP1-like 3
    NP_565604.1
    • SKP1-like 3 (SK3); FUNCTIONS IN: ubiquitin-protein ligase activity, protein binding; INVOLVED IN: ubiquitin-dependent protein catabolic process; LOCATED IN: cellular_component unknown; EXPRESSED IN: sepal, seed coat, pedicel, valve; CONTAINS InterPro DOMAIN/s: E3 ubiquitin ligase, SCF complex, Skp subunit (InterPro:IPR016897), SKP1 component, dimerisation (InterPro:IPR016072), SKP1 component (InterPro:IPR001232), BTB/POZ fold (InterPro:IPR011333), SKP1 component, POZ (InterPro:IPR016073); BEST Arabidopsis thaliana protein match is: SKP1-like 4 (TAIR:AT1G20140.1); Has 1425 Blast hits to 1421 proteins in 267 species: Archae - 0; Bacteria - 0; Metazoa - 551; Fungi - 177; Plants - 528; Viruses - 11; Other Eukaryotes - 158 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      10948747..10949626 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_128129.2 → NP_565604.1  SKP1-like 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_565604.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9SL93
      UniProtKB/TrEMBL
      A0A178VV27, A0A5S9X1C2, A0A654EW47
      Conserved Domains (2) summary
      cd18322
      Location:7 → 128
      BTB_POZ_SKP1; BTB (Broad-Complex, Tramtrack and Bric a brac) /POZ (poxvirus and zinc finger) domain found in S-phase kinase-associated protein 1 (SKP1) and similar proteins
      pfam01466
      Location:115 → 161
      Skp1; Skp1 family, dimerization domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SL93.1

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