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    LAX2 uncharacterized protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 816640, updated on 18-Sep-2024

    Summary

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    Official Symbol
    LAX2
    Official Full Name
    uncharacterized protein
    Primary source
    TAIR:AT2G21050
    Locus tag
    AT2G21050
    See related
    Araport:AT2G21050
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F26H11.19; F26H11_19; like AUXIN RESISTANT 2
    Summary
    Encodes LAX2 (LIKE AUXIN RESISTANT), a member of the AUX1 LAX family of auxin influx carriers. Required for the establishment of embryonic root cell organization.
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    Genomic context

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    See LAX2 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    6
    Sequence:
    Chromosome: 2; NC_003071.7 (9034056..9036636)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene Calcium-dependent lipid-binding (CaLB domain) family protein Neighboring gene Rhodanese/Cell cycle control phosphatase superfamily protein Neighboring gene glycine-rich protein 2B Neighboring gene methyltransferase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A role for LAX2 in regulating xylem development and lateral-vein symmetry in the leaf. Moreno-Piovano GS, et al. Ann Bot, 2017 Oct 17. PMID 28981582, Free PMC Article
    2. Auxin influx importers modulate serration along the leaf margin. Kasprzewska A, et al. Plant J, 2015 Aug. PMID 26111009, Free PMC Article
    3. AUX/LAX genes encode a family of auxin influx transporters that perform distinct functions during Arabidopsis development. Péret B, et al. Plant Cell, 2012 Jul. PMID 22773749, Free PMC Article
    4. Auxin influx carriers control vascular patterning and xylem differentiation in Arabidopsis thaliana. Fàbregas N, et al. PLoS Genet, 2015 Apr. PMID 25922946, Free PMC Article
    5. The AUX1 LAX family of auxin influx carriers is required for the establishment of embryonic root cell organization in Arabidopsis thaliana. Ugartechea-Chirino Y, et al. Ann Bot, 2010 Feb. PMID 19952011, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. role in regulating xylem development and lateral-vein symmetry in the leaf
      Title: A role for LAX2 in regulating xylem development and lateral-vein symmetry in the leaf.
    2. Data report that three of these genes (AUX1, LAX1 and LAX2) show specific and dynamic patterns of expression during early leaf development
      Title: Auxin influx importers modulate serration along the leaf margin.
    3. we observed fewer and more spaced vascular bundles in quadruple mutants plants of the auxin influx carriers aux1lax1lax2lax3
      Title: Auxin influx carriers control vascular patterning and xylem differentiation in Arabidopsis thaliana.
    4. LAX2 regulates vascular patterning in cotyledons.
      Title: AUX/LAX genes encode a family of auxin influx transporters that perform distinct functions during Arabidopsis development.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_127675.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables amino acid transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within cotyledon vascular tissue pattern formation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to nematode HEP PubMed 
    acts_upstream_of_or_within root cap development IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within somatic embryogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    NP_179701.1
    • like AUXIN RESISTANT 2 (LAX2); CONTAINS InterPro DOMAIN/s: Amino acid transporter, transmembrane (InterPro:IPR013057); BEST Arabidopsis thaliana protein match is: like AUX1 3 (TAIR:AT1G77690.1); Has 1017 Blast hits to 1012 proteins in 134 species: Archae - 0; Bacteria - 2; Metazoa - 94; Fungi - 224; Plants - 668; Viruses - 0; Other Eukaryotes - 29 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      9034056..9036636
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_127675.3 → NP_179701.1  uncharacterized protein AT2G21050 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_179701.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9S836
      UniProtKB/TrEMBL
      A0A178VQ86, A0A5S9X065
      Conserved Domains (1) summary
      PLN03074
      Location:2 → 461
      PLN03074; auxin influx permease; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9S836.1

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