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    TPD1 tapetum determinant 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 2745725, updated on 18-Sep-2024

    Summary

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    Official Symbol
    TPD1
    Official Full Name
    tapetum determinant 1
    Primary source
    TAIR:AT4G24972
    Locus tag
    AT4G24972
    See related
    Araport:AT4G24972
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    TAPETUM DETERMINANT 1
    Summary
    Encodes a novel small protein which is similar to proteins of unknown function from other plant species. TPD1 is involved in cell specification during anther and pollen development. Identified in a screen for male steriles. Mutants lack tapetal cells and have an increased number of microsporocytes. Expressed in flower buds, leaves and young seedlings. In anthers, TPD1 is expressed throughout pollen development in parietal cells and sporocytes. Physically interacts with the LRR kinase EMS1 and that interaction results in phosphorylation of TPD1.
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    Genomic context

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    See TPD1 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    4
    Sequence:
    Chromosome: 4; NC_003075.7 (12837353..12840230)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene HVA22 homologue D Neighboring gene Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase family protein Neighboring gene Plant self-incompatibility protein S1 family Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Ectopic expression of TAPETUM DETERMINANT1 affects ovule development in Arabidopsis. Huang J, et al. J Exp Bot, 2016 Mar. PMID 26685185
    2. Tapetum determinant1 is required for cell specialization in the Arabidopsis anther. Yang SL, et al. Plant Cell, 2003 Dec. PMID 14615601, Free PMC Article
    3. Control of Anther Cell Differentiation by the Small Protein Ligand TPD1 and Its Receptor EMS1 in Arabidopsis. Huang J, et al. PLoS Genet, 2016 Aug. PMID 27537183, Free PMC Article
    4. Signaling of cell fate determination by the TPD1 small protein and EMS1 receptor kinase. Jia G, et al. Proc Natl Acad Sci U S A, 2008 Feb 12. PMID 18250314, Free PMC Article
    5. Overexpression of TAPETUM DETERMINANT1 alters the cell fates in the Arabidopsis carpel and tapetum via genetic interaction with excess microsporocytes1/extra sporogenous cells. Yang SL, et al. Plant Physiol, 2005 Sep. PMID 16055681, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Analyses of the expressions and localizations of TPD1 and EMS1, ectopic expression of TPD1, experimental missorting of TPD1, and ablation of microsporocytes yielded results suggesting that the precursors of microsporocyte/microsporocyte-derived TPD1 and pre-tapetal-cell-localized EMS1 initially promote the periclinal division of secondary parietal cells and then determine one of the two daughter cells
      Title: Control of Anther Cell Differentiation by the Small Protein Ligand TPD1 and Its Receptor EMS1 in Arabidopsis.
    2. these results provide insight into the molecular mechanism by which TPD1-EMS1 signaling controls plant development possibly via regulation of auxin signaling and cell-cycle genes
      Title: Ectopic expression of TAPETUM DETERMINANT1 affects ovule development in Arabidopsis.
    3. Genetic analysis showed that the activation of cell division in the transgenic carpels of A. thaliana by TPD1 was dependent on EMS1/EXS, as it did not happen in the ems1/exs mutant.
      Title: Overexpression of TAPETUM DETERMINANT1 alters the cell fates in the Arabidopsis carpel and tapetum via genetic interaction with excess microsporocytes1/extra sporogenous cells.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_202883.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within anther development IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within cell fate determination IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    tapetum determinant 1
    NP_974612.1
    • TAPETUM DETERMINANT 1 (TPD1); FUNCTIONS IN: molecular_function unknown; INVOLVED IN: cell fate determination, anther development; LOCATED IN: endomembrane system; EXPRESSED IN: microsporocyte, floral meristem, flower, anther, leaf; EXPRESSED DURING: seedling growth; BEST Arabidopsis thaliana protein match is: unknown protein (TAIR:AT1G32583.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      12837353..12840230
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_202883.3 → NP_974612.1  tapetum determinant 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_974612.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q6TLJ2
      UniProtKB/TrEMBL
      A0A178V0R1
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6TLJ2.1

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