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    cntln centlein, centrosomal protein [ Danio rerio (zebrafish) ]

    Gene ID: 799510, updated on 2-Nov-2024

    Summary

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    Official Symbol
    cntlnprovided by ZNC
    Official Full Name
    centlein, centrosomal proteinprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-090313-409
    See related
    Ensembl:ENSDARG00000033345 AllianceGenome:ZFIN:ZDB-GENE-090313-409
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    si:dkeyp-9c8.1; si:ch211-2i17.1
    Summary
    Predicted to be involved in centriole-centriole cohesion and protein localization to organelle. Predicted to be active in centriole and centrosome. Orthologous to human CNTLN (centlein). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See cntln in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    27
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 1 NC_007112.7 (26823590..27014888, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 1 NC_007112.6 (26133732..26321165, complement)

    Chromosome 1 - NC_007112.7Genomic Context describing neighboring genes Neighboring gene forkhead box E1 Neighboring gene SH3 domain containing GRB2 like 2a, endophilin A1 Neighboring gene uncharacterized LOC101882912 Neighboring gene basonuclin zinc finger protein 2 Neighboring gene si:ch211-127n13.2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Transcriptomic analyses reveal novel genes with sexually dimorphic expression in the zebrafish gonad and brain. Sreenivasan R, et al. PLoS One, 2008 Mar 12. PMID 18335061, Free PMC Article
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    involved_in centriole-centriole cohesion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein localization to organelle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in centriole IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in centrosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    centlein; centlein, centrosomal protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007112.7 Reference GRCz11 Primary Assembly

      Range
      26823590..27014888 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_068221311.1 → XP_068077412.1  centlein isoform X3

      Related
      ENSDARP00000149036.1, ENSDART00000192087.1

    2. XM_068221310.1 → XP_068077411.1  centlein isoform X2

    3. XM_001922094.7 → XP_001922129.3  centlein isoform X1

      See identical proteins and their annotated locations for XP_001922129.3

      UniProtKB/TrEMBL
      A0A8M1QKQ5, F1QNE3, F1QX00
      Related
      ENSDARP00000122164.2, ENSDART00000147414.4
      Conserved Domains (1) summary
      TIGR02168
      Location:310 → 1010
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    4. XM_068221309.1 → XP_068077410.1  centlein isoform X1

      Related
      ENSDARP00000154169.1, ENSDART00000187248.1

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394485.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      868..167191 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_068218009.1 → XP_068074110.1  centlein isoform X5

    2. XM_021471204.2 → XP_021326879.1  centlein isoform X4

      UniProtKB/TrEMBL
      A0A8M9PPU9
      Conserved Domains (1) summary
      cl25732
      Location:310 → 996
      SMC_N; RecF/RecN/SMC N terminal domain

    3. XM_068218008.1 → XP_068074109.1  centlein isoform X4

    Reference GRCz11 ALT_DRER_TU_2

    Genomic

    1. NW_018395217.1 Reference GRCz11 ALT_DRER_TU_2

      Range
      20489..42785 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_068219147.1 → XP_068075248.1  centlein isoform X6

    Nucleotide Protein Strain
    Heading Accession and Version

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