dpm2 dolichyl-phosphate mannosyltransferase subunit 2, regulatory [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: dpm2provided by ZNC
Official Full Name: dolichyl-phosphate mannosyltransferase subunit 2, regulatoryprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-9093
See related: Ensembl:ENSDARG00000095623 AllianceGenome:ZFIN:ZDB-GENE-030131-9093
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: wu:fa99c01; zgc:112514
Summary: Predicted to enable enzyme regulator activity. Acts upstream of or within muscle structure development. Predicted to be located in endoplasmic reticulum membrane. Predicted to be part of dolichol-phosphate-mannose synthase complex. Is expressed in brain; cloaca; pronephric duct; solid lens vesicle; and vertical myoseptum. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation Iu. Orthologous to human DPM2 (dolichyl-phosphate mannosyltransferase subunit 2, regulatory). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 5

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	5	NC_007116.7 (31714352..31716713, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	5	NC_007116.6 (31114199..31116560, complement)

Chromosome 5 - NC_007116.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables enzyme regulator activity	IBA Inferred from Biological aspect of Ancestor more info
enables enzyme regulator activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in GPI anchor biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within dolichol metabolic process	IEA Inferred from Electronic Annotation more info
involved_in dolichol metabolic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within muscle structure development	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in protein glycosylation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of dolichol-phosphate-mannose synthase complex	IBA Inferred from Biological aspect of Ancestor more info
located_in endoplasmic reticulum	IEA Inferred from Electronic Annotation more info
located_in endoplasmic reticulum membrane	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: dolichol phosphate-mannose biosynthesis regulatory protein

Names: dolichol-phosphate (beta-D) mannosyltransferase 2; dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit

NP_001116318.1

EC 2.4.1.83

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

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These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.