mpeg1.3 macrophage expressed 1, tandem duplicate 3 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: mpeg1.3provided by ZNC
Official Full Name: macrophage expressed 1, tandem duplicate 3provided by ZNC
Primary source: ZFIN:ZDB-GENE-081105-5
See related: Ensembl:ENSDARG00000078569 AllianceGenome:ZFIN:ZDB-GENE-081105-5
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: si:ch211-247l22.3
Summary: Predicted to be involved in defense response to bacterium. Predicted to act upstream of or within adaptive immune response. Predicted to be located in phagocytic vesicle membrane. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Orthologous to human MPEG1 (macrophage expressed 1). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 8

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	8	NC_007119.7 (29655948..29658171, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	8	NC_007119.6 (29646716..29648939, complement)

Chromosome 8 - NC_007119.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by ZFIN

Process	Evidence Code	Pubs
acts_upstream_of_or_within adaptive immune response	IEA Inferred from Electronic Annotation more info
involved_in defense response to bacterium	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within immune system process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasmic vesicle	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in phagocytic vesicle membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: macrophage expressed 1, tandem duplicate 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001123310.1 → NP_001116782.1 macrophage expressed 1, tandem duplicate 3 precursor

Status: PROVISIONAL

Source sequence(s)

AL807792

UniProtKB/TrEMBL

A0A8M1NIM6, B0R063

Related

ENSDARP00000122072.1, ENSDART00000147755.2

Conserved Domains (1) summary

pfam01823
Location:125 → 340

MACPF; MAC/Perforin domain