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    snx20 sorting nexin 20 [ Danio rerio (zebrafish) ]

    Gene ID: 794759, updated on 17-Aug-2024

    Summary

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    Official Symbol
    snx20provided by ZNC
    Official Full Name
    sorting nexin 20provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-100806-1
    See related
    Ensembl:ENSDARG00000045554 AllianceGenome:ZFIN:ZDB-GENE-100806-1
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Summary
    Predicted to enable phosphatidylinositol phosphate binding activity. Predicted to act upstream of or within protein transport. Predicted to be located in membrane. Predicted to be active in early endosome membrane. Orthologous to human SNX20 (sorting nexin 20). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    human mouse all
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    Genomic context

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    See snx20 in Genome Data Viewer
    Location:
    chromosome: 25
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 25 NC_007136.7 (35957569..35963297, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 25 NC_007136.6 (35452647..35458298, complement)

    Chromosome 25 - NC_007136.7Genomic Context describing neighboring genes Neighboring gene hydroxysteroid (17-beta) dehydrogenase 2 Neighboring gene uncharacterized LOC110438402 Neighboring gene M-phase phosphoprotein 6 Neighboring gene spalt-like transcription factor 1b Neighboring gene retinoblastoma-like 2 (p130)

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. An antiapoptotic role of sorting nexin 7 is required for liver development in zebrafish. Xu L, et al. Hepatology, 2012 Jun. PMID 22213104
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables phosphatidylinositol binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phosphatidylinositol phosphate binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in early endosome membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in endosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    sorting nexin-20

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007136.7 Reference GRCz11 Primary Assembly

      Range
      35957569..35963297 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_009298207.3 → XP_009296482.1  sorting nexin-20 isoform X2

      UniProtKB/TrEMBL
      A0A8M3APX6
      Conserved Domains (1) summary
      cl02563
      Location:65 → 178
      PX_domain; The Phox Homology domain, a phosphoinositide binding module

    2. XM_005163188.4 → XP_005163245.1  sorting nexin-20 isoform X1

      See identical proteins and their annotated locations for XP_005163245.1

      UniProtKB/TrEMBL
      A0A2R9YJQ2, A0A8M2BA68
      Related
      ENSDART00000153919.2
      Conserved Domains (1) summary
      cl02563
      Location:69 → 182
      PX_domain; The Phox Homology domain, a phosphoinositide binding module

    3. XM_009298206.3 → XP_009296481.1  sorting nexin-20 isoform X1

      See identical proteins and their annotated locations for XP_009296481.1

      UniProtKB/TrEMBL
      A0A2R9YJQ2, A0A8M2BA68
      Related
      ENSDARP00000127957.1, ENSDART00000153612.3
      Conserved Domains (1) summary
      cl02563
      Location:69 → 182
      PX_domain; The Phox Homology domain, a phosphoinositide binding module
    Nucleotide Protein
    Heading Accession and Version

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