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    Pramel49 PRAME like 49 [ Mus musculus (house mouse) ]

    Gene ID: 666187, updated on 9-Aug-2024

    Summary

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    Official Symbol
    Pramel49provided by MGI
    Official Full Name
    PRAME like 49provided by MGI
    Primary source
    MGI:MGI:3779772
    See related
    Ensembl:ENSMUSG00000094043 AllianceGenome:MGI:3779772
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm7971
    Summary
    Predicted to enable ubiquitin ligase-substrate adaptor activity. Predicted to act upstream of or within protein ubiquitination. Predicted to be part of Cul2-RING ubiquitin ligase complex. Orthologous to several human genes including PRAMEF1 (PRAME family member 1); PRAMEF10 (PRAME family member 10); and PRAMEF11 (PRAME family member 11). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

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    See Pramel49 in Genome Data Viewer
    Location:
    5 E3; 5 47.29 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (95738694..95742721, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (95590835..95594862, complement)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene PRAME like 48 Neighboring gene PRAME like 57 Neighboring gene predicted gene 6348 Neighboring gene predicted gene 3302 Neighboring gene PRAME like 54 Neighboring gene PRAME like 50

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables ubiquitin-like ligase-substrate adaptor activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    part_of Cul2-RING ubiquitin ligase complex ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    PRAME family member 8-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      95738694..95742721 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_982184.5 → XP_987278.1  PRAME family member 8-like

      See identical proteins and their annotated locations for XP_987278.1

      UniProtKB/TrEMBL
      A0AAG1GHN1, J3QMM8, L7N204
      Related
      ENSMUSP00000084169.6, ENSMUST00000086950.6
      Conserved Domains (1) summary
      sd00031
      Location:273 → 298
      LRR_1; leucine-rich repeat [structural motif]
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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