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    ndufb11 NADH:ubiquinone oxidoreductase subunit B11 [ Danio rerio (zebrafish) ]

    Gene ID: 562219, updated on 28-Oct-2024

    Summary

    Official Symbol
    ndufb11provided by ZNC
    Official Full Name
    NADH:ubiquinone oxidoreductase subunit B11provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050309-25
    See related
    Ensembl:ENSDARG00000043467 AllianceGenome:ZFIN:ZDB-GENE-050309-25
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    im:6897973; si:dkey-6n6.4
    Summary
    Acts upstream of or within heart development and vasculature development. Predicted to be located in membrane. Predicted to be part of respiratory chain complex I. Is expressed in several structures, including alar plate midbrain region; digestive system; intestinal bulb primordium; optic tectum; and pectoral fin. Human ortholog(s) of this gene implicated in linear skin defects with multiple congenital anomalies 3 and nuclear type mitochondrial complex I deficiency 30. Orthologous to human NDUFB11 (NADH:ubiquinone oxidoreductase subunit B11). [provided by Alliance of Genome Resources, Oct 2024]
    Orthologs
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    Genomic context

    See ndufb11 in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 8 NC_007119.7 (14180064..14184423, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 8 NC_007119.6 (14142359..14146718, complement)

    Chromosome 8 - NC_007119.7Genomic Context describing neighboring genes Neighboring gene si:dkey-6n6.1 Neighboring gene thiamin pyrophosphokinase 2 Neighboring gene ras homolog gene family, member Aa Neighboring gene DEF6 guanine nucleotide exchange factor a Neighboring gene SIN3 transcription regulator family member B

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within heart development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within vasculature development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    part_of respiratory chain complex I IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial
    Names
    NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001044981.1NP_001038446.1  NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial

      Status: PROVISIONAL

      Source sequence(s)
      BX004884
      UniProtKB/TrEMBL
      A0A8M1N9R9, Q1LYN0
      Related
      ENSDARP00000063816.6, ENSDART00000063817.7
      Conserved Domains (1) summary
      pfam10183
      Location:26129
      ESSS; ESSS subunit of NADH:ubiquinone oxidoreductase (complex I)

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007119.7 Reference GRCz11 Primary Assembly

      Range
      14180064..14184423 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)