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    ST8SIA5 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 [ Bos taurus (domestic cattle) ]

    Gene ID: 497020, updated on 4-Oct-2024

    Summary

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    Official Symbol
    ST8SIA5provided by VGNC
    Official Full Name
    ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5provided by VGNC
    Primary source
    VGNC:VGNC:54494
    See related
    Ensembl:ENSBTAG00000001770
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    SIAT8E
    Orthologs
    human mouse all
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    Genomic context

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    See ST8SIA5 in Genome Data Viewer
    Location:
    chromosome: 24
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 24 NC_037351.1 (46407835..46485864, complement)

    Chromosome 24 - NC_037351.1Genomic Context describing neighboring genes Neighboring gene ring finger protein 165 Neighboring gene ribosomal protein L39-like pseudogene Neighboring gene lipoxygenase homology PLAT domains 1 Neighboring gene small ribosomal subunit protein eS25-like Neighboring gene protein inhibitor of activated STAT 2 Neighboring gene small ribosomal subunit protein uS12-like

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037351.1 Chromosome 24 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The animal sialyltransferases and sialyltransferase-related genes: a phylogenetic approach. Harduin-Lepers A, et al. Glycobiology, 2005 Aug. PMID 15843597
    2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in N-glycan processing IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in oligosaccharide metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein glycosylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    alpha-2,8-sialyltransferase 8E
    Names
    sialyltransferase 8 (alpha-2, 8-sialyltransferase) E
    NP_001179803.1
    XP_024839955.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001192874.2 → NP_001179803.1  alpha-2,8-sialyltransferase 8E

      Status: VALIDATED

      Source sequence(s)
      AAFC03029969, AAFC03048728, AJ868432
      UniProtKB/TrEMBL
      Q5NDF9
      Related
      ENSBTAP00000057992.1, ENSBTAT00000070064.1
      Conserved Domains (1) summary
      pfam00777
      Location:117 → 370
      Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037351.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      46407835..46485864 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024984187.2 → XP_024839955.1  alpha-2,8-sialyltransferase 8E isoform X1

      UniProtKB/TrEMBL
      F1N2J4, Q5NDF9
      Related
      ENSBTAP00000002317.6, ENSBTAT00000002317.7
      Conserved Domains (1) summary
      pfam00777
      Location:153 → 406
      Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)
    Nucleotide Protein Strain
    Heading Accession and Version

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