U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    CXCR1 C-X-C motif chemokine receptor 1 [ Gallus gallus (chicken) ]

    Gene ID: 430652, updated on 17-Aug-2024

    Summary

    Go to the top of the page Help
    Symbol
    CXCR1provided by CGNC
    Full Name
    C-X-C motif chemokine receptor 1provided by CGNC
    Primary source
    CGNC:15413
    See related
    Ensembl:ENSGALG00010019250
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Also known as
    CXCR2; IL8RB
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See CXCR1 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 7 NC_052538.1 (22210751..22213598)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 7 NC_052579.1 (22130403..22133249)

    Chromosome 7 - NC_052538.1Genomic Context describing neighboring genes Neighboring gene transmembrane BAX inhibitor motif containing 1 Neighboring gene paroxysmal nonkinesigenic dyskinesia Neighboring gene angio associated migratory cell protein Neighboring gene actin related protein 2/3 complex subunit 2 Neighboring gene RUN and FYVE domain containing 4 Neighboring gene tensin 1 Neighboring gene uncharacterized LOC101749755

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. cCXCR1 is a receptor for cIL-8 (9E3/cCAF) and its N- and C-terminal peptides and is also activated by hIL-8 (CXCL8). Li QJ, et al. J Leukoc Biol, 2005 Mar. PMID 15576419
    2. Isolation and characterization of a new chemokine receptor gene, the putative chicken CXCR1. Li QJ, et al. Gene, 2000 Oct 31. PMID 11080597
    3. Re-evaluation of chicken CXCR1 determines the true gene structure: CXCLi1 (K60) and CXCLi2 (CAF/interleukin-8) are ligands for this receptor. Poh TY, et al. J Biol Chem, 2008 Jun 13. PMID 18417470
    4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The chicken CXCR1 Receptor is activated by chicken IL-8 and its N- and C-terminal peptides and whether it responds to human IL-8.
      Title: cCXCR1 is a receptor for cIL-8 (9E3/cCAF) and its N- and C-terminal peptides and is also activated by hIL-8 (CXCL8).
    2. CXCLi1 (K60) and CXCLi2 (CAF/interleukin-8) look equally like orthologues of human CXCL8 and are ligands for chicken CXCR1
      Title: Re-evaluation of chicken CXCR1 determines the true gene structure: CXCLi1 (K60) and CXCLi2 (CAF/interleukin-8) are ligands for this receptor.
    Submit: New GeneRIF Correction

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables C-X-C chemokine receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in immune response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in neutrophil chemotaxis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    C-X-C chemokine receptor type 2
    Names
    G-protein coupled receptor
    chemokine (C-X-C motif) receptor 1
    chemokine (C-X-C motif) receptor 2
    interleukin 8 receptor, beta
    putative C-X-C chemokine receptor type 1, CXCR1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001282432.2 → NP_001269361.1  C-X-C chemokine receptor type 2

      See identical proteins and their annotated locations for NP_001269361.1

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000236
      UniProtKB/TrEMBL
      Q334G8
      Conserved Domains (1) summary
      pfam00001
      Location:78 → 313
      7tm_1; 7 transmembrane receptor (rhodopsin family)

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052538.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      22210751..22213598
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015289858.4 → XP_015145344.1  C-X-C chemokine receptor type 2 isoform X1

      UniProtKB/TrEMBL
      Q334G8
      Related
      ENSGALP00010027706.1, ENSGALT00010046535.1
      Conserved Domains (1) summary
      pfam00001
      Location:78 → 313
      7tm_1; 7 transmembrane receptor (rhodopsin family)

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052579.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      22130403..22133249
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046921667.1 → XP_046777623.1  C-X-C chemokine receptor type 2 isoform X1

      UniProtKB/TrEMBL
      Q334G8

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001031591.1: Suppressed sequence

      Description
      NM_001031591.1: This RefSeq was permanently suppressed because there were insertions and deletions compared to available sequence data. These differences resulted in frame-shifts and a protein that is not supported by available protein (homology) data.
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut