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    NOVA1 NOVA alternative splicing regulator 1 [ Gallus gallus (chicken) ]

    Gene ID: 423300, updated on 10-Oct-2024

    Summary

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    Symbol
    NOVA1provided by CGNC
    Full Name
    NOVA alternative splicing regulator 1provided by CGNC
    Primary source
    CGNC:7484
    See related
    Ensembl:ENSGALG00010007328
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See NOVA1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 5 NC_052536.1 (32294160..32475901, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 5 NC_052577.1 (32271394..32453855, complement)

    Chromosome 5 - NC_052536.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC112531814 Neighboring gene U1 spliceosomal RNA Neighboring gene uncharacterized LOC124418373 Neighboring gene uncharacterized LOC124417979 Neighboring gene uncharacterized LOC121111042 Neighboring gene microRNA 3532 Neighboring gene uncharacterized LOC121113251

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. ESTs from brain and testis of White Leghorn and red junglefowl: annotation, bioinformatic classification of unknown transcripts and analysis of expression levels. Savolainen P, et al. Cytogenet Genome Res, 2005. PMID 16093725
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables mRNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mRNA splicing, via spliceosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of alternative mRNA splicing, via spliceosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    RNA-binding protein Nova-1
    Names
    neuro-oncological ventral antigen 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001199712.2 → NP_001186641.1  RNA-binding protein Nova-1 isoform 1

      See identical proteins and their annotated locations for NP_001186641.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1)
      Source sequence(s)
      JAENSK010000215
      UniProtKB/TrEMBL
      R4GG35
      Conserved Domains (3) summary
      cd09031
      Location:422 → 492
      KH-I_NOVA_rpt3; third type I K homology (KH) RNA-binding domain found in the family of neuro-oncological ventral antigen (Nova)
      cd22435
      Location:49 → 121
      KH-I_NOVA_rpt1; first type I K homology (KH) RNA-binding domain found in the family of neuro-oncological ventral antigen (Nova)
      cd22436
      Location:172 → 241
      KH-I_NOVA_rpt2; second type I K homology (KH) RNA-binding domain found in the family of neuro-oncological ventral antigen (Nova)

    2. NM_001199713.2 → NP_001186642.1  RNA-binding protein Nova-1 isoform 2

      See identical proteins and their annotated locations for NP_001186642.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 3' coding region, compared to variant 1. The resulting protein (isoform 2) is shorter, compared to isoform 1.
      Source sequence(s)
      JAENSK010000215
      UniProtKB/TrEMBL
      R4GH08
      Conserved Domains (3) summary
      cd09031
      Location:398 → 468
      KH-I_NOVA_rpt3; third type I K homology (KH) RNA-binding domain found in the family of neuro-oncological ventral antigen (Nova)
      cd22435
      Location:49 → 121
      KH-I_NOVA_rpt1; first type I K homology (KH) RNA-binding domain found in the family of neuro-oncological ventral antigen (Nova)
      cd22436
      Location:148 → 217
      KH-I_NOVA_rpt2; second type I K homology (KH) RNA-binding domain found in the family of neuro-oncological ventral antigen (Nova)

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052536.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      32294160..32475901 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046941754.1 → XP_046797710.1  RNA-binding protein Nova-1 isoform X1

    2. XM_040700982.2 → XP_040556916.1  RNA-binding protein Nova-1 isoform X2

      UniProtKB/TrEMBL
      A0A8V0XD43
      Conserved Domains (2) summary
      cd09031
      Location:300 → 370
      KH-I_NOVA_rpt3; third type I K homology (KH) RNA-binding domain found in the family of neuro-oncological ventral antigen (Nova)
      cd22436
      Location:50 → 119
      KH-I_NOVA_rpt2; second type I K homology (KH) RNA-binding domain found in the family of neuro-oncological ventral antigen (Nova)

    3. XM_046941755.1 → XP_046797711.1  RNA-binding protein Nova-1 isoform X2

    4. XM_046941756.1 → XP_046797712.1  RNA-binding protein Nova-1 isoform X2

    5. XM_040700984.2 → XP_040556918.1  RNA-binding protein Nova-1 isoform X3

      UniProtKB/TrEMBL
      A0A8V0XSJ7
      Related
      ENSGALP00010009665.1, ENSGALT00010017480.1
      Conserved Domains (1) summary
      cd22435
      Location:49 → 121
      KH-I_NOVA_rpt1; first type I K homology (KH) RNA-binding domain found in the family of neuro-oncological ventral antigen (Nova)

    RNA

    1. XR_001466732.4 RNA Sequence

    2. XR_001466730.4 RNA Sequence

    3. XR_005860043.2 RNA Sequence

    4. XR_005860042.2 RNA Sequence

    5. XR_001466731.4 RNA Sequence

    6. XR_001466729.4 RNA Sequence

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052577.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      32271394..32453855 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046918531.1 → XP_046774487.1  RNA-binding protein Nova-1 isoform X1

    2. XM_046918532.1 → XP_046774488.1  RNA-binding protein Nova-1 isoform X2

    3. XM_046918533.1 → XP_046774489.1  RNA-binding protein Nova-1 isoform X2

    4. XM_046918534.1 → XP_046774490.1  RNA-binding protein Nova-1 isoform X2

    5. XM_046918535.1 → XP_046774491.1  RNA-binding protein Nova-1 isoform X3

    RNA

    1. XR_006934698.1 RNA Sequence

    2. XR_006934697.1 RNA Sequence

    3. XR_006934702.1 RNA Sequence

    4. XR_006934700.1 RNA Sequence

    5. XR_006934701.1 RNA Sequence

    6. XR_006934699.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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