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    PDCD6IP programmed cell death 6 interacting protein [ Gallus gallus (chicken) ]

    Gene ID: 420725, updated on 17-Aug-2024

    Summary

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    Symbol
    PDCD6IPprovided by CGNC
    Full Name
    programmed cell death 6 interacting proteinprovided by CGNC
    Primary source
    CGNC:9128
    See related
    Ensembl:ENSGALG00010018338
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See PDCD6IP in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 2 NC_052533.1 (44744454..44777259)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 2 NC_052574.1 (44794150..44826934)

    Chromosome 2 - NC_052533.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101751546 Neighboring gene uncharacterized LOC107052522 Neighboring gene uncharacterized LOC107052521 Neighboring gene cAMP regulated phosphoprotein 21 Neighboring gene microRNA 1607

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Alix and ALG-2 are involved in tumor necrosis factor receptor 1-induced cell death. Mahul-Mellier AL, et al. J Biol Chem, 2008 Dec 12. PMID 18936101, Free PMC Article
    2. Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Caldwell RB, et al. Genome Biol, 2005. PMID 15642098, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Alix and ALG-2 are new actors of the TNF-R1 pathway [Alix]
      Title: Alix and ALG-2 are involved in tumor necrosis factor receptor 1-induced cell death.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mitotic cytokinesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in endosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    programmed cell death 6-interacting protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001030993.2 → NP_001026164.1  programmed cell death 6-interacting protein

      See identical proteins and their annotated locations for NP_001026164.1

      Status: PROVISIONAL

      Source sequence(s)
      JAENSK010000037
      UniProtKB/TrEMBL
      F1NG09, Q5ZJ70
      Related
      ENSGALP00010026332.1, ENSGALT00010044269.1
      Conserved Domains (3) summary
      cd09235
      Location:364 → 702
      V_Alix; Middle V-domain of mammalian Alix and related domains are dimerization and protein interaction modules
      cd09240
      Location:2 → 349
      BRO1_Alix; Protein-interacting, N-terminal, Bro1-like domain of mammalian Alix and related domains
      pfam13949
      Location:416 → 705
      ALIX_LYPXL_bnd; ALIX V-shaped domain binding to HIV

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052533.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      44744454..44777259
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015281533.4 → XP_015137019.2  programmed cell death 6-interacting protein isoform X1

      Conserved Domains (2) summary
      cd09235
      Location:364 → 702
      V_Alix; Middle V-domain of mammalian Alix and related domains are dimerization and protein interaction modules
      cd09240
      Location:2 → 349
      BRO1_Alix; Protein-interacting, N-terminal, Bro1-like domain of mammalian Alix and related domains

    2. XM_015281534.4 → XP_015137020.2  programmed cell death 6-interacting protein isoform X2

      Conserved Domains (2) summary
      cd09235
      Location:359 → 697
      V_Alix; Middle V-domain of mammalian Alix and related domains are dimerization and protein interaction modules
      cd09240
      Location:2 → 344
      BRO1_Alix; Protein-interacting, N-terminal, Bro1-like domain of mammalian Alix and related domains

    3. XM_040682928.2 → XP_040538862.1  programmed cell death 6-interacting protein isoform X3

      Conserved Domains (2) summary
      cd09235
      Location:359 → 697
      V_Alix; Middle V-domain of mammalian Alix and related domains are dimerization and protein interaction modules
      cd09240
      Location:2 → 344
      BRO1_Alix; Protein-interacting, N-terminal, Bro1-like domain of mammalian Alix and related domains

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052574.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      44794150..44826934
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046911293.1 → XP_046767249.1  programmed cell death 6-interacting protein isoform X1

    2. XM_046911294.1 → XP_046767250.1  programmed cell death 6-interacting protein isoform X2

    3. XM_046911295.1 → XP_046767251.1  programmed cell death 6-interacting protein isoform X3

    Nucleotide Protein Strain
    Heading Accession and Version

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