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    FLI1 Fli-1 proto-oncogene, ETS transcription factor [ Gallus gallus (chicken) ]

    Gene ID: 419723, updated on 10-Oct-2024

    Summary

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    Symbol
    FLI1provided by CGNC
    Full Name
    Fli-1 proto-oncogene, ETS transcription factorprovided by CGNC
    Primary source
    CGNC:51069
    See related
    Ensembl:ENSGALG00010023337
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See FLI1 in Genome Data Viewer
    Location:
    chromosome: 24
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 24 NC_052555.1 (1026337..1115058)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 24 NC_052596.1 (985796..1074662)

    Chromosome 24 - NC_052555.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC419722 Neighboring gene v-ets avian erythroblastosis virus E26 oncogene homolog 1 Neighboring gene Potassium inwardly rectifying channel subfamily J member 5 Neighboring gene potassium inwardly rectifying channel subfamily J member 1 Neighboring gene Rho GTPase activating protein 33

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Caldwell RB, et al. Genome Biol, 2005. PMID 15642098, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Friend leukemia integration 1 transcription factor
    Names
    Friend leukemia virus integration 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001030908.2 → NP_001026079.2  Friend leukemia integration 1 transcription factor

      Status: PROVISIONAL

      Source sequence(s)
      JAENSK010000341
      UniProtKB/TrEMBL
      A0A1D5PED3, Q5ZKX5
      Related
      ENSGALP00010034609.1, ENSGALT00010056915.1
      Conserved Domains (2) summary
      cd08541
      Location:114 → 204
      SAM_PNT-FLI-1; Sterile alpha motif (SAM)/Pointed domain of friend leukemia integration 1 transcription activator
      smart00413
      Location:260 → 343
      ETS; erythroblast transformation specific domain

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052555.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      1026337..1115058
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046903746.1 → XP_046759702.1  Friend leukemia integration 1 transcription factor isoform X2

      UniProtKB/TrEMBL
      A0A8V0ZST3

    2. XM_015297986.4 → XP_015153472.1  Friend leukemia integration 1 transcription factor isoform X1

      UniProtKB/TrEMBL
      Q5ZKX5
      Conserved Domains (2) summary
      cd08541
      Location:130 → 220
      SAM_PNT-FLI-1; Sterile alpha motif (SAM)/Pointed domain of friend leukemia integration 1 transcription activator
      smart00413
      Location:276 → 359
      ETS; erythroblast transformation specific domain

    3. XM_015297987.4 → XP_015153473.1  Friend leukemia integration 1 transcription factor isoform X2

      UniProtKB/TrEMBL
      A0A8V0ZST3, Q5ZKX5
      Related
      ENSGALP00010034612.1, ENSGALT00010056923.1
      Conserved Domains (2) summary
      cd08541
      Location:121 → 211
      SAM_PNT-FLI-1; Sterile alpha motif (SAM)/Pointed domain of friend leukemia integration 1 transcription activator
      smart00413
      Location:267 → 350
      ETS; erythroblast transformation specific domain

    4. XM_046903747.1 → XP_046759703.1  Friend leukemia integration 1 transcription factor isoform X3

      UniProtKB/TrEMBL
      A0A8V0ZMJ7
      Related
      ENSGALP00010034610.1, ENSGALT00010056919.1

    5. XM_046903748.1 → XP_046759704.1  Friend leukemia integration 1 transcription factor isoform X4

      Conserved Domains (2) summary
      cd08541
      Location:81 → 171
      SAM_PNT-FLI-1; Sterile alpha motif (SAM)/Pointed domain of friend leukemia integration 1 transcription activator
      smart00413
      Location:227 → 310
      ETS; erythroblast transformation specific domain

    6. XM_046903749.1 → XP_046759705.1  Friend leukemia integration 1 transcription factor isoform X4

      Related
      ENSGALP00010034600.1, ENSGALT00010056901.1
      Conserved Domains (2) summary
      cd08541
      Location:81 → 171
      SAM_PNT-FLI-1; Sterile alpha motif (SAM)/Pointed domain of friend leukemia integration 1 transcription activator
      smart00413
      Location:227 → 310
      ETS; erythroblast transformation specific domain

    7. XM_025143183.3 → XP_024998951.1  Friend leukemia integration 1 transcription factor isoform X4

      UniProtKB/TrEMBL
      Q5ZKX5
      Conserved Domains (2) summary
      cd08541
      Location:81 → 171
      SAM_PNT-FLI-1; Sterile alpha motif (SAM)/Pointed domain of friend leukemia integration 1 transcription activator
      smart00413
      Location:227 → 310
      ETS; erythroblast transformation specific domain

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052596.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      985796..1074662
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046932327.1 → XP_046788283.1  Friend leukemia integration 1 transcription factor isoform X2

      UniProtKB/TrEMBL
      A0A8V0ZST3

    2. XM_046932325.1 → XP_046788281.1  Friend leukemia integration 1 transcription factor isoform X1

    3. XM_046932326.1 → XP_046788282.1  Friend leukemia integration 1 transcription factor isoform X2

      UniProtKB/TrEMBL
      A0A8V0ZST3

    4. XM_046932328.1 → XP_046788284.1  Friend leukemia integration 1 transcription factor isoform X3

      UniProtKB/TrEMBL
      A0A8V0ZMJ7

    5. XM_046932329.1 → XP_046788285.1  Friend leukemia integration 1 transcription factor isoform X4

      Conserved Domains (2) summary
      cd08541
      Location:81 → 171
      SAM_PNT-FLI-1; Sterile alpha motif (SAM)/Pointed domain of friend leukemia integration 1 transcription activator
      smart00413
      Location:227 → 310
      ETS; erythroblast transformation specific domain

    6. XM_046932331.1 → XP_046788287.1  Friend leukemia integration 1 transcription factor isoform X4

      Conserved Domains (2) summary
      cd08541
      Location:81 → 171
      SAM_PNT-FLI-1; Sterile alpha motif (SAM)/Pointed domain of friend leukemia integration 1 transcription activator
      smart00413
      Location:227 → 310
      ETS; erythroblast transformation specific domain

    7. XM_046932330.1 → XP_046788286.1  Friend leukemia integration 1 transcription factor isoform X4

      Conserved Domains (2) summary
      cd08541
      Location:81 → 171
      SAM_PNT-FLI-1; Sterile alpha motif (SAM)/Pointed domain of friend leukemia integration 1 transcription activator
      smart00413
      Location:227 → 310
      ETS; erythroblast transformation specific domain
    Nucleotide Protein Strain
    Heading Accession and Version

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