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    GUCY2C guanylate cyclase 2C [ Gallus gallus (chicken) ]

    Gene ID: 417968, updated on 17-Aug-2024

    Summary

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    Symbol
    GUCY2Cprovided by CGNC
    Full Name
    guanylate cyclase 2Cprovided by CGNC
    Primary source
    CGNC:8973
    See related
    Ensembl:ENSGALG00010011323
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See GUCY2C in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    28
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 1 NC_052532.1 (48983778..49029397, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 1 NC_052573.1 (49283186..49328960, complement)

    Chromosome 1 - NC_052532.1Genomic Context describing neighboring genes Neighboring gene activating transcription factor 7 interacting protein Neighboring gene uncharacterized LOC121109323 Neighboring gene phospholipase B domain containing 1 Neighboring gene intraflagellar transport 56 Neighboring gene ubinuclein 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables guanylate cyclase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables peptide receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cGMP biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in receptor guanylyl cyclase signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    heat-stable enterotoxin receptor
    Names
    guanylate cyclase 2C (heat stable enterotoxin receptor)
    XP_025010803.1
    XP_040516440.1
    XP_040516442.1
    XP_040516443.1
    XP_040524381.1
    XP_416207.3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052532.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      48983778..49029397 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040668447.2 → XP_040524381.1  heat-stable enterotoxin receptor isoform X2

      UniProtKB/TrEMBL
      A0A1D5PI12
      Related
      ENSGALP00010015404.1, ENSGALT00010027073.1
      Conserved Domains (3) summary
      smart00044
      Location:752 → 944
      CYCc; Adenylyl- / guanylyl cyclase, catalytic domain
      cl10011
      Location:33 → 414
      Periplasmic_Binding_Protein_type1; Type 1 periplasmic binding fold superfamily
      cl21453
      Location:479 → 714
      PKc_like; Protein Kinases, catalytic domain

    2. XM_416207.8 → XP_416207.3  heat-stable enterotoxin receptor isoform X1

      UniProtKB/TrEMBL
      E1BZE2
      Related
      ENSGALP00010015406.1, ENSGALT00010027075.1
      Conserved Domains (6) summary
      cd06369
      Location:33 → 414
      PBP1_GC_C_enterotoxin_receptor; Ligand-binding domain of the membrane guanylyl cyclase C
      smart00044
      Location:787 → 979
      CYCc; Adenylyl- / guanylyl cyclase, catalytic domain
      cd14044
      Location:479 → 749
      PK_GC-C; Pseudokinase domain of the membrane Guanylate Cyclase receptor, GC-C
      pfam00211
      Location:814 → 1001
      Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
      pfam01094
      Location:55 → 371
      ANF_receptor; Receptor family ligand binding region
      pfam07714
      Location:501 → 744
      Pkinase_Tyr; Protein tyrosine kinase

    3. XM_025155035.3 → XP_025010803.1  heat-stable enterotoxin receptor isoform X3

      Conserved Domains (3) summary
      smart00044
      Location:602 → 794
      CYCc; Adenylyl- / guanylyl cyclase, catalytic domain
      cd14044
      Location:294 → 564
      PK_GC-C; Pseudokinase domain of the membrane Guanylate Cyclase receptor, GC-C
      cl10011
      Location:19 → 229
      Periplasmic_Binding_Protein_Type_1; Type 1 periplasmic binding fold superfamily

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052573.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      49283186..49328960 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040660508.2 → XP_040516442.1  heat-stable enterotoxin receptor isoform X2

      Conserved Domains (3) summary
      smart00044
      Location:752 → 944
      CYCc; Adenylyl- / guanylyl cyclase, catalytic domain
      cl10011
      Location:33 → 414
      Periplasmic_Binding_Protein_type1; Type 1 periplasmic binding fold superfamily
      cl21453
      Location:479 → 714
      PKc_like; Protein Kinases, catalytic domain

    2. XM_040660506.2 → XP_040516440.1  heat-stable enterotoxin receptor isoform X1

      Conserved Domains (3) summary
      smart00044
      Location:787 → 979
      CYCc; Adenylyl- / guanylyl cyclase, catalytic domain
      cd14044
      Location:479 → 749
      PK_GC-C; Pseudokinase domain of the membrane Guanylate Cyclase receptor, GC-C
      cl10011
      Location:33 → 414
      Periplasmic_Binding_Protein_type1; Type 1 periplasmic binding fold superfamily

    3. XM_040660509.2 → XP_040516443.1  heat-stable enterotoxin receptor isoform X3

      Conserved Domains (3) summary
      smart00044
      Location:602 → 794
      CYCc; Adenylyl- / guanylyl cyclase, catalytic domain
      cd14044
      Location:294 → 564
      PK_GC-C; Pseudokinase domain of the membrane Guanylate Cyclase receptor, GC-C
      cl10011
      Location:19 → 229
      Periplasmic_Binding_Protein_type1; Type 1 periplasmic binding fold superfamily
    Nucleotide Protein
    Heading Accession and Version

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