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    STRA8 stimulated by retinoic acid 8 [ Gallus gallus (chicken) ]

    Gene ID: 417938, updated on 17-Aug-2024

    Summary

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    Symbol
    STRA8provided by CGNC
    Full Name
    stimulated by retinoic acid 8provided by CGNC
    Primary source
    CGNC:8909
    See related
    Ensembl:ENSGALG00010010177
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
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    Genomic context

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    See STRA8 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 1 NC_052532.1 (47930610..47946526, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 1 NC_052573.1 (48227440..48243351, complement)

    Chromosome 1 - NC_052532.1Genomic Context describing neighboring genes Neighboring gene CCR4-NOT transcription complex subunit 4 Neighboring gene uncharacterized LOC107053813 Neighboring gene solute carrier family 23 member 1-like Neighboring gene WD repeat domain 91 Neighboring gene uncharacterized LOC121109486 Neighboring gene chromosome 7 open reading frame 49 Neighboring gene transmembrane protein 140

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. CRISPR/Cas9 mediated chicken Stra8 gene knockout and inhibition of male germ cell differentiation. Zhang Y, et al. PLoS One, 2017. PMID 28234938, Free PMC Article
    2. The Induction Effect of Am80 and TSA on ESC Differentiation via Regulation of Stra8 in Chicken. Zhang Y, et al. PLoS One, 2015. PMID 26606052, Free PMC Article
    3. miR-31 Regulates Spermatogonial Stem Cells Meiosis via Targeting Stra8. Wang Y, et al. J Cell Biochem, 2017 Dec. PMID 28543764
    4. Jun-mediated lncRNA-IMS promotes the meiosis of chicken spermatogonial stem cells via gga-miR-31-5p/stra8. Wang Y, et al. Mol Reprod Dev, 2023 May. PMID 36966461
    5. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Jun-mediated lncRNA-IMS promotes the meiosis of chicken spermatogonial stem cells via gga-miR-31-5p/stra8.
      Title: Jun-mediated lncRNA-IMS promotes the meiosis of chicken spermatogonial stem cells via gga-miR-31-5p/stra8.
    2. The results showed that miR-31 regulates meiosis of Spermatogonial Stem Cells via targeting Stra8 in vitro and in vivo.
      Title: miR-31 Regulates Spermatogonial Stem Cells Meiosis via Targeting Stra8.
    3. the Cas9/gRNA system is shown to mediate Stra8 gene knockout in chicken DF-1 cells, which begins to provide information on the molecular regulation mechanism of Stra8 gene during the differentiating process from embryonic stem cells into male germ cells in vitro
      Title: CRISPR/Cas9 mediated chicken Stra8 gene knockout and inhibition of male germ cell differentiation.
    4. The regulatory elements of the Stra8 promoter are involved in regulating differentiation of chicken embryonic stem cells.
      Title: The Induction Effect of Am80 and TSA on ESC Differentiation via Regulation of Stra8 in Chicken.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein dimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cellular response to retinoic acid IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in meiotic cell cycle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    stimulated by retinoic acid gene 8 protein homolog; stimulated by retinoic acid gene 8 protein
    Names
    stimulated by retinoic acid gene 8 homolog
    stimulated by retinoic acid protein 8

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052532.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      47930610..47946526 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046914811.1 → XP_046770767.1  stimulated by retinoic acid gene 8 protein homolog isoform X1

    2. XM_040667922.2 → XP_040523856.1  stimulated by retinoic acid gene 8 protein homolog isoform X4

      UniProtKB/TrEMBL
      J7GKU7

    3. XM_040667905.2 → XP_040523839.1  stimulated by retinoic acid gene 8 protein isoform X3

      UniProtKB/TrEMBL
      A0A8V0XZP6, A0A8V0Y496
      Related
      ENSGALP00010013780.1, ENSGALT00010024199.1

    4. XM_040667893.2 → XP_040523827.1  stimulated by retinoic acid gene 8 protein homolog isoform X2

      Conserved Domains (1) summary
      cd00083
      Location:40 → 80
      bHLH_SF; basic Helix Loop Helix (bHLH) domain superfamily

    5. XM_040667913.2 → XP_040523847.1  stimulated by retinoic acid gene 8 protein isoform X3

      UniProtKB/TrEMBL
      A0A8V0XZP6, A0A8V0Y496

    6. XM_015289566.4 → XP_015145052.2  stimulated by retinoic acid gene 8 protein isoform X3

      UniProtKB/TrEMBL
      A0A8V0XZP6, A0A8V0Y496

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052573.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      48227440..48243351 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046909348.1 → XP_046765304.1  stimulated by retinoic acid gene 8 protein homolog isoform X1

    2. XM_040662177.2 → XP_040518111.1  stimulated by retinoic acid gene 8 protein homolog isoform X4

      UniProtKB/TrEMBL
      J7GKU7

    3. XM_040662175.2 → XP_040518109.1  stimulated by retinoic acid gene 8 protein isoform X3

      UniProtKB/TrEMBL
      A0A8V0XZP6, A0A8V0Y496

    4. XM_040662173.2 → XP_040518107.1  stimulated by retinoic acid gene 8 protein homolog isoform X2

      Conserved Domains (1) summary
      cd00083
      Location:40 → 80
      bHLH_SF; basic Helix Loop Helix (bHLH) domain superfamily

    5. XM_040662176.2 → XP_040518110.1  stimulated by retinoic acid gene 8 protein isoform X3

      UniProtKB/TrEMBL
      A0A8V0XZP6, A0A8V0Y496

    6. XM_040662174.2 → XP_040518108.1  stimulated by retinoic acid gene 8 protein isoform X3

      UniProtKB/TrEMBL
      A0A8V0XZP6, A0A8V0Y496
    Nucleotide Protein
    Heading Accession and Version

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