ric8b RIC8 guanine nucleotide exchange factor B [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: ric8bprovided by ZNC
Official Full Name: RIC8 guanine nucleotide exchange factor Bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-6435
See related: Ensembl:ENSDARG00000005972 AllianceGenome:ZFIN:ZDB-GENE-030131-6435
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: synbl; fj97c10; wu:fj97c10
Summary: Predicted to enable G-protein alpha-subunit binding activity; guanyl-nucleotide exchange factor activity; and protein folding chaperone. Acts upstream of or within pigment cell development. Predicted to be active in cytoplasm and plasma membrane. Orthologous to human RIC8B (RIC8 guanine nucleotide exchange factor B). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 18

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	18	NC_007129.7 (15295950..15329471, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	18	NC_007129.6 (15327438..15360959, complement)

Chromosome 18 - NC_007129.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

ha2836 (e-PCR)
- UniSTS:515599

G41095 (e-PCR)
- UniSTS:38321

fj97c10.x1 (e-PCR)
- UniSTS:200423

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables G-protein alpha-subunit binding	IBA Inferred from Biological aspect of Ancestor more info
enables G-protein alpha-subunit binding	ISS Inferred from Sequence or Structural Similarity more info
enables guanyl-nucleotide exchange factor activity	IBA Inferred from Biological aspect of Ancestor more info
enables guanyl-nucleotide exchange factor activity	IEA Inferred from Electronic Annotation more info
enables guanyl-nucleotide exchange factor activity	ISS Inferred from Sequence or Structural Similarity more info
enables protein folding chaperone	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
involved_in G protein-coupled receptor signaling pathway	IBA Inferred from Biological aspect of Ancestor more info
involved_in G protein-coupled receptor signaling pathway	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within pigment cell development	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in sensory perception of smell	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
is_active_in plasma membrane	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: synembryn-B

Names: resistance to inhibitors of cholinesterase 8 homolog B; synembryn like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.