Mpv17l2 MPV17 mitochondrial membrane protein-like 2 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Mpv17l2provided by MGI
Official Full Name: MPV17 mitochondrial membrane protein-like 2provided by MGI
Primary source: MGI:MGI:2681846
See related: Ensembl:ENSMUSG00000035559 AllianceGenome:MGI:2681846
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Fksg24
Summary: Predicted to be involved in mitochondrial ribosome assembly and positive regulation of mitochondrial translation. Located in mitochondrion. Is expressed in bone; genitourinary system; and gut. Orthologous to human MPV17L2 (MPV17 mitochondrial inner membrane protein like 2). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Broad expression in adrenal adult (RPKM 118.7), stomach adult (RPKM 57.9) and 26 other tissues See more
Orthologs: human all
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Genomic context

Location:: 8 B3.3; 8 34.15 cM

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	8	NC_000074.7 (71211295..71213589, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	8	NC_000074.6 (70758649..70760932, complement)

Chromosome 8 - NC_000074.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (2)
Targeted (3)

General gene information

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Markers

X72966 (e-PCR)
- UniSTS:185762

RH133798 (e-PCR)
- UniSTS:217081

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in mitochondrial ribosome assembly	IBA Inferred from Biological aspect of Ancestor more info
involved_in mitochondrial ribosome assembly	IEA Inferred from Electronic Annotation more info
involved_in mitochondrial ribosome assembly	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of mitochondrial translation	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of mitochondrial translation	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrial inner membrane	ISO Inferred from Sequence Orthology more info
located_in mitochondrial inner membrane	ISS Inferred from Sequence or Structural Similarity more info
part_of mitochondrial large ribosomal subunit	ISO Inferred from Sequence Orthology more info
part_of mitochondrial large ribosomal subunit	ISS Inferred from Sequence or Structural Similarity more info
located_in mitochondrion	HDA more info	PubMed
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: mpv17-like protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_183170.2 → NP_898993.1 mpv17-like protein 2

See identical proteins and their annotated locations for NP_898993.1

Status: PROVISIONAL

Source sequence(s)

CAAA01070179

Consensus CDS

CCDS22380.1

UniProtKB/Swiss-Prot

Q3THH2, Q80UR1, Q8VIK2

Related

ENSMUSP00000037929.9, ENSMUST00000038626.10

Conserved Domains (1) summary

pfam04117
Location:124 → 186

Mpv17_PMP22; Mpv17 / PMP22 family

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

NC_000074.7 Reference GRCm39 C57BL/6J

Range

71211295..71213589 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_011242299.3 → XP_011240601.1 mpv17-like protein 2 isoform X1

Conserved Domains (1) summary

pfam04117
Location:28 → 89

Mpv17_PMP22; Mpv17 / PMP22 family