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    susd5 sushi domain containing 5 [ Danio rerio (zebrafish) ]

    Gene ID: 101886789, updated on 27-Mar-2024

    Summary

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    Official Symbol
    susd5provided by ZNC
    Official Full Name
    sushi domain containing 5provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-120215-196
    See related
    Ensembl:ENSDARG00000088277 AllianceGenome:ZFIN:ZDB-GENE-120215-196
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    si:ch211-207c15.6
    Summary
    Predicted to enable hyaluronic acid binding activity. Predicted to be involved in Notch signaling pathway. Predicted to act upstream of or within cell adhesion. Predicted to be located in membrane. Predicted to be integral component of membrane. Orthologous to human SUSD5 (sushi domain containing 5). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    human mouse all
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    Genomic context

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    See susd5 in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 19 NC_007130.7 (42629476..42651867, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 19 NC_007130.6 (43060059..43082209, complement)

    Chromosome 19 - NC_007130.7Genomic Context describing neighboring genes Neighboring gene FKBP prolyl isomerase 9 Neighboring gene cartilage associated protein Neighboring gene uncharacterized LOC103909275 Neighboring gene F-box and leucine-rich repeat protein 2 Neighboring gene cytoplasmic linker associated protein 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Crtap and p3h1 knock out zebrafish support defective collagen chaperoning as the cause of their osteogenesis imperfecta phenotype. Tonelli F, et al. Matrix Biol, 2020 Aug. PMID 32173581
    2. Hypoxia-inducible factor 3 is an oxygen-dependent transcription activator and regulates a distinct transcriptional response to hypoxia. Zhang P, et al. Cell Rep, 2014 Mar 27. PMID 24613356
    3. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables hyaluronic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in Notch signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within cell adhesion IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    sushi domain-containing protein 5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007130.7 Reference GRCz11 Primary Assembly

      Range
      42629476..42651867 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005159753.4 → XP_005159810.1  sushi domain-containing protein 5

      See identical proteins and their annotated locations for XP_005159810.1

      UniProtKB/TrEMBL
      A0A8M3ASV6, E7EYM4
      Conserved Domains (3) summary
      cd12094
      Location:577 → 613
      TM_ErbB2; Transmembrane domain of ErbB2, a Protein Tyrosine Kinase
      pfam00084
      Location:129 → 186
      Sushi; Sushi repeat (SCR repeat)
      cl02612
      Location:28 → 122
      Link_Domain; The link domain is a hyaluronan (HA)-binding domain. It functions to mediate adhesive interactions during inflammatory leukocyte homing and tumor metastasis. It is found in the CD44 receptor and in human TSG-6. TSG-6 is the protein product of the tumor ...

    2. XM_009294430.3 → XP_009292705.1  sushi domain-containing protein 5

      See identical proteins and their annotated locations for XP_009292705.1

      UniProtKB/TrEMBL
      A0A8M3ASV6, E7EYM4
      Related
      ENSDARP00000109477.2, ENSDART00000123360.3
      Conserved Domains (3) summary
      cd12094
      Location:577 → 613
      TM_ErbB2; Transmembrane domain of ErbB2, a Protein Tyrosine Kinase
      pfam00084
      Location:129 → 186
      Sushi; Sushi repeat (SCR repeat)
      cl02612
      Location:28 → 122
      Link_Domain; The link domain is a hyaluronan (HA)-binding domain. It functions to mediate adhesive interactions during inflammatory leukocyte homing and tumor metastasis. It is found in the CD44 receptor and in human TSG-6. TSG-6 is the protein product of the tumor ...
    Nucleotide Protein
    Heading Accession and Version

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