atad2b ATPase family AAA domain containing 2B [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: atad2bprovided by ZNC
Official Full Name: ATPase family AAA domain containing 2Bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-110411-210
See related: Ensembl:ENSDARG00000060537 AllianceGenome:ZFIN:ZDB-GENE-110411-210
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: si:ch73-97d3.2
Summary: Predicted to enable ATP hydrolysis activity; chromatin binding activity; and histone binding activity. Predicted to be involved in nucleosome assembly; nucleosome disassembly; and transcription initiation-coupled chromatin remodeling. Predicted to be active in nucleus. Orthologous to human ATAD2B (ATPase family AAA domain containing 2B). [provided by Alliance of Genome Resources, Oct 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 20

Exon count:: 28

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	20	NC_007131.7 (44582291..44796770)
105	previous assembly	GRCz10 (GCF_000002035.5)	20	NC_007131.6 (44684166..44887672)

Chromosome 20 - NC_007131.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables ATP hydrolysis activity	IBA Inferred from Biological aspect of Ancestor more info
enables ATP hydrolysis activity	IEA Inferred from Electronic Annotation more info
enables chromatin binding	IBA Inferred from Biological aspect of Ancestor more info
enables histone binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in anatomical structure morphogenesis	IEA Inferred from Electronic Annotation more info
involved_in nucleosome assembly	IBA Inferred from Biological aspect of Ancestor more info
involved_in nucleosome disassembly	IBA Inferred from Biological aspect of Ancestor more info
involved_in transcription initiation-coupled chromatin remodeling	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: ATPase family AAA domain-containing protein 2B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001365966.1 → NP_001352895.1 ATPase family AAA domain-containing protein 2B isoform 1

Status: VALIDATED

Source sequence(s)

FP103080, LO018343, LO018347

Conserved Domains (3) summary

cd05528
Location:957 → 1068

Bromo_AAA; Bromodomain; sub-family co-occurring with AAA domains. Bromodomains are 110 amino acid long domains, that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine. The structure(2DKW) in this ...

COG0464
Location:341 → 657

SpoVK; AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms]

cl21455
Location:767 → 879

P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
NM_001365967.1 → NP_001352896.1 ATPase family AAA domain-containing protein 2B isoform 2

Status: VALIDATED

Source sequence(s)

FP103080, LO018343, LO018347

UniProtKB/TrEMBL

A0A8M1REM4, E7FE14

Related

ENSDARP00000079851.5, ENSDART00000085416.6

Conserved Domains (3) summary

cd05528
Location:942 → 1053

Bromo_AAA; Bromodomain; sub-family co-occurring with AAA domains. Bromodomains are 110 amino acid long domains, that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine. The structure(2DKW) in this ...

COG0464
Location:326 → 642

SpoVK; AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms]

cl21455
Location:752 → 864

P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases