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    cd59b CD59 molecule (CD59 blood group) b [ Danio rerio (zebrafish) ]

    Gene ID: 100003678, updated on 17-Sep-2024

    Summary

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    Official Symbol
    cd59bprovided by ZNC
    Official Full Name
    CD59 molecule (CD59 blood group) bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-131127-232
    See related
    Ensembl:ENSDARG00000089255 AllianceGenome:ZFIN:ZDB-GENE-131127-232
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    si:ch211-286c4.6
    Summary
    Human ortholog(s) of this gene implicated in colorectal carcinoma and ovarian cancer. Orthologous to human CD59 (CD59 molecule (CD59 blood group)). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See cd59b in Genome Data Viewer
    Location:
    chromosome: 25
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 25 NC_007136.7 (7679448..7686211, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 25 NC_007136.6 (7555356..7562284, complement)

    Chromosome 25 - NC_007136.7Genomic Context describing neighboring genes Neighboring gene Bet1 golgi vesicular membrane trafficking protein-like Neighboring gene potassium inwardly rectifying channel subfamily J member 11, like Neighboring gene PR domain containing 11 Neighboring gene PHD finger protein 21Ab

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. The Ly6/uPAR protein Bouncer is necessary and sufficient for species-specific fertilization. Herberg S, et al. Science, 2018 Sep 7. PMID 30190407, Free PMC Article
    2. Identification and expression of a novel member of Ly-6 superfamily in zebrafish Denio rerio. Ji D, et al. Dev Genes Evol, 2012 Apr. PMID 22415300
    3. Single cell sequencing of radial glia progeny reveals the diversity of newborn neurons in the adult zebrafish brain. Lange C, et al. Development, 2020 Jan 9. PMID 31908317, Free PMC Article
    4. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
    5. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in side of membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    CD59 glycoprotein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007136.7 Reference GRCz11 Primary Assembly

      Range
      7679448..7686211 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_009297782.4 → XP_009296057.1  CD59 glycoprotein isoform X2

      See identical proteins and their annotated locations for XP_009296057.1

      UniProtKB/TrEMBL
      A0A8M1Q769, X1WEP8
      Related
      ENSDARP00000128699.1, ENSDART00000157267.3
      Conserved Domains (1) summary
      cl10471
      Location:22 → 93
      LU; Ly-6 antigen / uPA receptor -like domain; occurs singly in GPI-linked cell-surface glycoproteins (Ly-6 family,CD59, thymocyte B cell antigen, Sgp-2) or as three-fold repeated domain in urokinase-type plasminogen activator receptor. Topology of these ...

    2. XM_001336753.8 → XP_001336789.2  CD59 glycoprotein isoform X2

      See identical proteins and their annotated locations for XP_001336789.2

      UniProtKB/TrEMBL
      A0A8M1Q769, X1WEP8
      Conserved Domains (1) summary
      cl10471
      Location:22 → 93
      LU; Ly-6 antigen / uPA receptor -like domain; occurs singly in GPI-linked cell-surface glycoproteins (Ly-6 family,CD59, thymocyte B cell antigen, Sgp-2) or as three-fold repeated domain in urokinase-type plasminogen activator receptor. Topology of these ...

    3. XM_009297781.4 → XP_009296056.1  CD59 glycoprotein isoform X1

      See identical proteins and their annotated locations for XP_009296056.1

      UniProtKB/TrEMBL
      A0A8M6YVZ7, E7F8K3
      Conserved Domains (1) summary
      cl10471
      Location:34 → 105
      LU; Ly-6 antigen / uPA receptor -like domain; occurs singly in GPI-linked cell-surface glycoproteins (Ly-6 family,CD59, thymocyte B cell antigen, Sgp-2) or as three-fold repeated domain in urokinase-type plasminogen activator receptor. Topology of these ...

    4. XM_009297780.4 → XP_009296055.1  CD59 glycoprotein isoform X1

      See identical proteins and their annotated locations for XP_009296055.1

      UniProtKB/TrEMBL
      A0A8M6YVZ7, E7F8K3
      Related
      ENSDARP00000128144.1, ENSDART00000155094.3
      Conserved Domains (1) summary
      cl10471
      Location:34 → 105
      LU; Ly-6 antigen / uPA receptor -like domain; occurs singly in GPI-linked cell-surface glycoproteins (Ly-6 family,CD59, thymocyte B cell antigen, Sgp-2) or as three-fold repeated domain in urokinase-type plasminogen activator receptor. Topology of these ...
    Nucleotide Protein
    Heading Accession and Version

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