U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    DSCAM DS cell adhesion molecule [ Canis lupus familiaris (dog) ]

    Gene ID: 487768, updated on 5-Mar-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    DSCAMprovided by VGNC
    Official Full Name
    DS cell adhesion moleculeprovided by VGNC
    Primary source
    VGNC:VGNC:40102
    See related
    Ensembl:ENSCAFG00845029877
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See DSCAM in Genome Data Viewer
    Location:
    chromosome: 31
    Exon count:
    33
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 31 NC_051835.1 (34180996..34914940, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 31 NC_006613.4 (33951978..34617540, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 31 NC_049252.1 (34548894..35278352, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 31 NC_049291.1 (34050877..34780483, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 31 NC_049772.1 (34056656..34784846, complement)

    Chromosome 31 - NC_051835.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119867024 Neighboring gene uncharacterized LOC119867072 Neighboring gene Purkinje cell protein 4 Neighboring gene uncharacterized LOC111093435 Neighboring gene uncharacterized LOC111093436 Neighboring gene uncharacterized LOC111093434 Neighboring gene uncharacterized LOC111093536 Neighboring gene uncharacterized LOC119867025 Neighboring gene uncharacterized LOC106558093 Neighboring gene uncharacterized LOC119867073

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables cell-cell adhesion mediator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in axon guidance IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in dendrite self-avoidance IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in homophilic cell adhesion via plasma membrane adhesion molecules IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in axon IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    Down syndrome cell adhesion molecule

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051835.1 Reference ROS_Cfam_1.0

      Range
      34180996..34914940 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038443552.1 → XP_038299480.1  Down syndrome cell adhesion molecule isoform X1

      UniProtKB/TrEMBL
      A0A8C0PL99, A0A8C0TRU5, A0A8I3Q4Z1
      Related
      ENSCAFP00845041637.1, ENSCAFT00845053030.1
      Conserved Domains (8) summary
      smart00408
      Location:239 → 300
      IGc2; Immunoglobulin C-2 Type
      cd00063
      Location:1380 → 1470
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam13927
      Location:1287 → 1363
      Ig_3; Immunoglobulin domain
      cd00096
      Location:406 → 409
      Ig; Ig strand A [structural motif]
      cd05734
      Location:689 → 784
      Ig_DSCAM; Immunoglobulin (Ig)-like domain of Down Syndrome Cell Adhesion molecule (DSCAM)
      cd05735
      Location:785 → 884
      Ig_DSCAM; Immunoglobulin (Ig) domain of Down Syndrome Cell Adhesion molecule (DSCAM)
      cd20958
      Location:504 → 593
      IgI_5_Dscam; Fifth immunoglobulin domain of the Drosophila melanogaster Dscam protein, and similar domains; a member of the I-set of IgSF domains
      cl11960
      Location:406 → 501
      Ig; Immunoglobulin domain

    2. XM_038443553.1 → XP_038299481.1  Down syndrome cell adhesion molecule isoform X2

      Conserved Domains (7) summary
      smart00408
      Location:239 → 300
      IGc2; Immunoglobulin C-2 Type
      cd00063
      Location:885 → 978
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd00096
      Location:406 → 409
      Ig; Ig strand A [structural motif]
      cd05734
      Location:689 → 784
      Ig_DSCAM; Immunoglobulin (Ig)-like domain of Down Syndrome Cell Adhesion molecule (DSCAM)
      cd05735
      Location:785 → 884
      Ig_DSCAM; Immunoglobulin (Ig) domain of Down Syndrome Cell Adhesion molecule (DSCAM)
      cd20958
      Location:504 → 593
      IgI_5_Dscam; Fifth immunoglobulin domain of the Drosophila melanogaster Dscam protein, and similar domains; a member of the I-set of IgSF domains
      cl11960
      Location:406 → 501
      Ig; Immunoglobulin domain

    3. XM_038443554.1 → XP_038299482.1  Down syndrome cell adhesion molecule isoform X3

      Conserved Domains (7) summary
      smart00408
      Location:239 → 300
      IGc2; Immunoglobulin C-2 Type
      cd00063
      Location:885 → 928
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd00096
      Location:406 → 409
      Ig; Ig strand A [structural motif]
      cd05734
      Location:689 → 784
      Ig_DSCAM; Immunoglobulin (Ig)-like domain of Down Syndrome Cell Adhesion molecule (DSCAM)
      cd05735
      Location:785 → 884
      Ig_DSCAM; Immunoglobulin (Ig) domain of Down Syndrome Cell Adhesion molecule (DSCAM)
      cd20958
      Location:504 → 593
      IgI_5_Dscam; Fifth immunoglobulin domain of the Drosophila melanogaster Dscam protein, and similar domains; a member of the I-set of IgSF domains
      cl11960
      Location:406 → 501
      Ig; Immunoglobulin domain

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049291.1 Alternate UMICH_Zoey_3.1

      Range
      34050877..34780483 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038517961.1 → XP_038373889.1  Down syndrome cell adhesion molecule isoform X1

      Conserved Domains (8) summary
      smart00408
      Location:239 → 300
      IGc2; Immunoglobulin C-2 Type
      cd00063
      Location:1380 → 1470
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam13927
      Location:1287 → 1363
      Ig_3; Immunoglobulin domain
      cd00096
      Location:406 → 409
      Ig; Ig strand A [structural motif]
      cd05734
      Location:689 → 784
      Ig_DSCAM; Immunoglobulin (Ig)-like domain of Down Syndrome Cell Adhesion molecule (DSCAM)
      cd05735
      Location:785 → 884
      Ig_DSCAM; Immunoglobulin (Ig) domain of Down Syndrome Cell Adhesion molecule (DSCAM)
      cd20958
      Location:504 → 593
      IgI_5_Dscam; Fifth immunoglobulin domain of the Drosophila melanogaster Dscam protein, and similar domains; a member of the I-set of IgSF domains
      cl11960
      Location:406 → 501
      Ig; Immunoglobulin domain

    2. XM_038517963.1 → XP_038373891.1  Down syndrome cell adhesion molecule isoform X2

      Conserved Domains (7) summary
      smart00408
      Location:239 → 300
      IGc2; Immunoglobulin C-2 Type
      cd00063
      Location:885 → 978
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd00096
      Location:406 → 409
      Ig; Ig strand A [structural motif]
      cd05734
      Location:689 → 784
      Ig_DSCAM; Immunoglobulin (Ig)-like domain of Down Syndrome Cell Adhesion molecule (DSCAM)
      cd05735
      Location:785 → 884
      Ig_DSCAM; Immunoglobulin (Ig) domain of Down Syndrome Cell Adhesion molecule (DSCAM)
      cd20958
      Location:504 → 593
      IgI_5_Dscam; Fifth immunoglobulin domain of the Drosophila melanogaster Dscam protein, and similar domains; a member of the I-set of IgSF domains
      cl11960
      Location:406 → 501
      Ig; Immunoglobulin domain

    3. XM_038517964.1 → XP_038373892.1  Down syndrome cell adhesion molecule isoform X3

      Conserved Domains (7) summary
      smart00408
      Location:239 → 300
      IGc2; Immunoglobulin C-2 Type
      cd00063
      Location:885 → 928
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd00096
      Location:406 → 409
      Ig; Ig strand A [structural motif]
      cd05734
      Location:689 → 784
      Ig_DSCAM; Immunoglobulin (Ig)-like domain of Down Syndrome Cell Adhesion molecule (DSCAM)
      cd05735
      Location:785 → 884
      Ig_DSCAM; Immunoglobulin (Ig) domain of Down Syndrome Cell Adhesion molecule (DSCAM)
      cd20958
      Location:504 → 593
      IgI_5_Dscam; Fifth immunoglobulin domain of the Drosophila melanogaster Dscam protein, and similar domains; a member of the I-set of IgSF domains
      cl11960
      Location:406 → 501
      Ig; Immunoglobulin domain

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049772.1 Alternate UNSW_CanFamBas_1.0

      Range
      34056656..34784846 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038645916.1 → XP_038501844.1  Down syndrome cell adhesion molecule isoform X1

      Conserved Domains (8) summary
      smart00408
      Location:239 → 300
      IGc2; Immunoglobulin C-2 Type
      cd00063
      Location:1380 → 1470
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam13927
      Location:1287 → 1363
      Ig_3; Immunoglobulin domain
      cd00096
      Location:406 → 409
      Ig; Ig strand A [structural motif]
      cd05734
      Location:689 → 784
      Ig_DSCAM; Immunoglobulin (Ig)-like domain of Down Syndrome Cell Adhesion molecule (DSCAM)
      cd05735
      Location:785 → 884
      Ig_DSCAM; Immunoglobulin (Ig) domain of Down Syndrome Cell Adhesion molecule (DSCAM)
      cd20958
      Location:504 → 593
      IgI_5_Dscam; Fifth immunoglobulin domain of the Drosophila melanogaster Dscam protein, and similar domains; a member of the I-set of IgSF domains
      cl11960
      Location:406 → 501
      Ig; Immunoglobulin domain

    2. XM_038645917.1 → XP_038501845.1  Down syndrome cell adhesion molecule isoform X2

      Conserved Domains (7) summary
      smart00408
      Location:239 → 300
      IGc2; Immunoglobulin C-2 Type
      cd00063
      Location:885 → 978
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd00096
      Location:406 → 409
      Ig; Ig strand A [structural motif]
      cd05734
      Location:689 → 784
      Ig_DSCAM; Immunoglobulin (Ig)-like domain of Down Syndrome Cell Adhesion molecule (DSCAM)
      cd05735
      Location:785 → 884
      Ig_DSCAM; Immunoglobulin (Ig) domain of Down Syndrome Cell Adhesion molecule (DSCAM)
      cd20958
      Location:504 → 593
      IgI_5_Dscam; Fifth immunoglobulin domain of the Drosophila melanogaster Dscam protein, and similar domains; a member of the I-set of IgSF domains
      cl11960
      Location:406 → 501
      Ig; Immunoglobulin domain

    3. XM_038645918.1 → XP_038501846.1  Down syndrome cell adhesion molecule isoform X3

      Conserved Domains (7) summary
      smart00408
      Location:239 → 300
      IGc2; Immunoglobulin C-2 Type
      cd00063
      Location:885 → 928
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd00096
      Location:406 → 409
      Ig; Ig strand A [structural motif]
      cd05734
      Location:689 → 784
      Ig_DSCAM; Immunoglobulin (Ig)-like domain of Down Syndrome Cell Adhesion molecule (DSCAM)
      cd05735
      Location:785 → 884
      Ig_DSCAM; Immunoglobulin (Ig) domain of Down Syndrome Cell Adhesion molecule (DSCAM)
      cd20958
      Location:504 → 593
      IgI_5_Dscam; Fifth immunoglobulin domain of the Drosophila melanogaster Dscam protein, and similar domains; a member of the I-set of IgSF domains
      cl11960
      Location:406 → 501
      Ig; Immunoglobulin domain

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049252.1 Alternate UU_Cfam_GSD_1.0

      Range
      34548894..35278352 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038581531.1 → XP_038437459.1  Down syndrome cell adhesion molecule isoform X1

      UniProtKB/TrEMBL
      A0A8C0PL99, A0A8C0TRU5, A0A8I3Q4Z1
      Conserved Domains (8) summary
      smart00408
      Location:239 → 300
      IGc2; Immunoglobulin C-2 Type
      cd00063
      Location:1380 → 1470
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam13927
      Location:1287 → 1363
      Ig_3; Immunoglobulin domain
      cd00096
      Location:406 → 409
      Ig; Ig strand A [structural motif]
      cd05734
      Location:689 → 784
      Ig_DSCAM; Immunoglobulin (Ig)-like domain of Down Syndrome Cell Adhesion molecule (DSCAM)
      cd05735
      Location:785 → 884
      Ig_DSCAM; Immunoglobulin (Ig) domain of Down Syndrome Cell Adhesion molecule (DSCAM)
      cd20958
      Location:504 → 593
      IgI_5_Dscam; Fifth immunoglobulin domain of the Drosophila melanogaster Dscam protein, and similar domains; a member of the I-set of IgSF domains
      cl11960
      Location:406 → 501
      Ig; Immunoglobulin domain

    2. XM_038581532.1 → XP_038437460.1  Down syndrome cell adhesion molecule isoform X2

      Conserved Domains (7) summary
      smart00408
      Location:239 → 300
      IGc2; Immunoglobulin C-2 Type
      cd00063
      Location:885 → 978
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd00096
      Location:406 → 409
      Ig; Ig strand A [structural motif]
      cd05734
      Location:689 → 784
      Ig_DSCAM; Immunoglobulin (Ig)-like domain of Down Syndrome Cell Adhesion molecule (DSCAM)
      cd05735
      Location:785 → 884
      Ig_DSCAM; Immunoglobulin (Ig) domain of Down Syndrome Cell Adhesion molecule (DSCAM)
      cd20958
      Location:504 → 593
      IgI_5_Dscam; Fifth immunoglobulin domain of the Drosophila melanogaster Dscam protein, and similar domains; a member of the I-set of IgSF domains
      cl11960
      Location:406 → 501
      Ig; Immunoglobulin domain

    3. XM_038581533.1 → XP_038437461.1  Down syndrome cell adhesion molecule isoform X3

      Conserved Domains (7) summary
      smart00408
      Location:239 → 300
      IGc2; Immunoglobulin C-2 Type
      cd00063
      Location:885 → 928
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd00096
      Location:406 → 409
      Ig; Ig strand A [structural motif]
      cd05734
      Location:689 → 784
      Ig_DSCAM; Immunoglobulin (Ig)-like domain of Down Syndrome Cell Adhesion molecule (DSCAM)
      cd05735
      Location:785 → 884
      Ig_DSCAM; Immunoglobulin (Ig) domain of Down Syndrome Cell Adhesion molecule (DSCAM)
      cd20958
      Location:504 → 593
      IgI_5_Dscam; Fifth immunoglobulin domain of the Drosophila melanogaster Dscam protein, and similar domains; a member of the I-set of IgSF domains
      cl11960
      Location:406 → 501
      Ig; Immunoglobulin domain

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006613.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      33951978..34617540 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038461728.1 → XP_038317656.1  Down syndrome cell adhesion molecule isoform X4

      UniProtKB/TrEMBL
      A0A8P0NC74
      Conserved Domains (6) summary
      cd00063
      Location:1268 → 1358
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam13927
      Location:1175 → 1251
      Ig_3; Immunoglobulin domain
      cd00096
      Location:446 → 449
      Ig; Ig strand A [structural motif]
      cd05734
      Location:729 → 824
      Ig_DSCAM; Immunoglobulin (Ig)-like domain of Down Syndrome Cell Adhesion molecule (DSCAM)
      cd20958
      Location:544 → 633
      IgI_5_Dscam; Fifth immunoglobulin domain of the Drosophila melanogaster Dscam protein, and similar domains; a member of the I-set of IgSF domains
      cl11960
      Location:446 → 541
      Ig; Immunoglobulin domain
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials