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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1977 2
1979 1
1984 2
1985 1
1986 2
1987 1
1988 4
1989 6
1990 2
1991 9
1992 7
1993 7
1994 5
1995 7
1996 11
1997 5
1998 15
1999 16
2000 16
2001 18
2002 15
2003 16
2004 13
2005 28
2006 24
2007 22
2008 20
2009 20
2010 23
2011 19
2012 27
2013 24
2014 36
2015 31
2016 27
2017 35
2018 32
2019 29
2020 34
2021 29
2022 27
2023 29
2024 7

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645 results

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Page 1
Pancreatic cancer epidemiology: understanding the role of lifestyle and inherited risk factors.
Klein AP. Klein AP. Nat Rev Gastroenterol Hepatol. 2021 Jul;18(7):493-502. doi: 10.1038/s41575-021-00457-x. Epub 2021 May 17. Nat Rev Gastroenterol Hepatol. 2021. PMID: 34002083 Free PMC article. Review.
Inherited genetic factors, although not directly modifiable, are an important component of pancreatic cancer risk, and include pathogenic variants in hereditary cancer genes, genes associated with hereditary pancreatitis, as well as common variants identified in genome-wid …
Inherited genetic factors, although not directly modifiable, are an important component of pancreatic cancer risk, and include pathog …
An update on peptide-based therapies for type 2 diabetes and obesity.
Bailey CJ, Flatt PR, Conlon JM. Bailey CJ, et al. Peptides. 2023 Mar;161:170939. doi: 10.1016/j.peptides.2023.170939. Epub 2023 Jan 3. Peptides. 2023. PMID: 36608818 Free article. Review.
These analogues herald an exciting new era in peptide-based therapy for type 2 diabetes (T2D) and obesity. Of note is the GLP-1R agonist semaglutide, available in oral and injectable formulations and in clinical trials combined with the long-acting amylin analogue, cagrili …
These analogues herald an exciting new era in peptide-based therapy for type 2 diabetes (T2D) and obesity. Of note is the GLP-1R agon …
The genetics of obesity: from discovery to biology.
Loos RJF, Yeo GSH. Loos RJF, et al. Nat Rev Genet. 2022 Feb;23(2):120-133. doi: 10.1038/s41576-021-00414-z. Epub 2021 Sep 23. Nat Rev Genet. 2022. PMID: 34556834 Free PMC article. Review.
The prevalence of obesity has tripled over the past four decades, imposing an enormous burden on people's health. Polygenic (or common) obesity and rare, severe, early-onset monogenic obesity are often polarized as distinct diseases. ...
The prevalence of obesity has tripled over the past four decades, imposing an enormous burden on people's health. Polygenic (or commo …
Genetic Determinants of Childhood Obesity.
Littleton SH, Berkowitz RI, Grant SFA. Littleton SH, et al. Mol Diagn Ther. 2020 Dec;24(6):653-663. doi: 10.1007/s40291-020-00496-1. Epub 2020 Oct 1. Mol Diagn Ther. 2020. PMID: 33006084 Free PMC article. Review.
Obesity represents a major health burden to both developed and developing countries. ...Non-syndromic cases of obesity can be further separated into rarer instances of monogenic obesity and much more common forms of polygenic obesity. ...
Obesity represents a major health burden to both developed and developing countries. ...Non-syndromic cases of obesity can be …
Epigenetic Transgenerational Inheritance of Obesity Susceptibility.
King SE, Skinner MK. King SE, et al. Trends Endocrinol Metab. 2020 Jul;31(7):478-494. doi: 10.1016/j.tem.2020.02.009. Epub 2020 Mar 24. Trends Endocrinol Metab. 2020. PMID: 32521235 Free PMC article. Review.
The prevalence of obesity and associated diseases has reached pandemic levels. Obesity is often associated with overnutrition and a sedentary lifestyle, but clearly other factors also increase the susceptibility of metabolic disease states. ...In this review, we dis …
The prevalence of obesity and associated diseases has reached pandemic levels. Obesity is often associated with overnutrition …
The epidemiology of venous thromboembolism.
Heit JA, Spencer FA, White RH. Heit JA, et al. J Thromb Thrombolysis. 2016 Jan;41(1):3-14. doi: 10.1007/s11239-015-1311-6. J Thromb Thrombolysis. 2016. PMID: 26780736 Free PMC article. Review.
VTE is a complex (multifactorial) disease, involving interactions between acquired or inherited predispositions to thrombosis and VTE risk factors, including increasing patient age and obesity, hospitalization for surgery or acute illness, nursing-home confinement, …
VTE is a complex (multifactorial) disease, involving interactions between acquired or inherited predispositions to thrombosis and VTE …
Prader-Willi Syndrome - Clinical Genetics, Diagnosis and Treatment Approaches: An Update.
Butler MG, Miller JL, Forster JL. Butler MG, et al. Curr Pediatr Rev. 2019;15(4):207-244. doi: 10.2174/1573396315666190716120925. Curr Pediatr Rev. 2019. PMID: 31333129 Free PMC article. Review.
Short stature and small hands/feet due to growth and other hormone deficiencies, hyperphagia and marked obesity occur in early childhood, if uncontrolled. Cognitive and behavioral problems (tantrums, compulsions, compulsive skin picking) are common. OBJECTIVE: Hyperphagia …
Short stature and small hands/feet due to growth and other hormone deficiencies, hyperphagia and marked obesity occur in early childh …
Genetics, epigenetics and transgenerational transmission of obesity in children.
Panera N, Mandato C, Crudele A, Bertrando S, Vajro P, Alisi A. Panera N, et al. Front Endocrinol (Lausanne). 2022 Nov 14;13:1006008. doi: 10.3389/fendo.2022.1006008. eCollection 2022. Front Endocrinol (Lausanne). 2022. PMID: 36452324 Free PMC article. Review.
The usual ineffectiveness of present therapies and failure of prevention campaigns triggered overtime a number of research studies which have unveiled some relevant aspects of obesity genetic and epigenetic inheritable profiles. These findings are revealing extremel …
The usual ineffectiveness of present therapies and failure of prevention campaigns triggered overtime a number of research studies which hav …
Polycystic Ovary Syndrome.
Azziz R. Azziz R. Obstet Gynecol. 2018 Aug;132(2):321-336. doi: 10.1097/AOG.0000000000002698. Obstet Gynecol. 2018. PMID: 29995717 Review.
Clinicians should clearly denote a patient's phenotype when making the diagnosis of PCOS. Polycystic ovary syndrome is a highly inherited complex polygenic, multifactorial disorder. Pathophysiologically abnormalities in gonadotropin secretion or action, ovarian folliculoge …
Clinicians should clearly denote a patient's phenotype when making the diagnosis of PCOS. Polycystic ovary syndrome is a highly inherited …
Exercise and Cystic Fibrosis.
Ding S, Zhong C. Ding S, et al. Adv Exp Med Biol. 2020;1228:381-391. doi: 10.1007/978-981-15-1792-1_26. Adv Exp Med Biol. 2020. PMID: 32342472 Review.
Cystic fibrosis (CF) is an autosomal recessive, inherited congenital disease caused by the mutation of the family autosomal CF gene, with cumulative exocrine secretion characterized by inflammation, tracheal remodeling, and mucus accumulation. ...Exercise is widely used to …
Cystic fibrosis (CF) is an autosomal recessive, inherited congenital disease caused by the mutation of the family autosomal CF gene, …
645 results