Comparison of EDTA and acid-citrate-dextrose collection tubes for detection of cytomegalovirus antigenemia and infectivity in leukocytes before and after storage

J Clin Microbiol. 1997 Jan;35(1):305-6. doi: 10.1128/jcm.35.1.305-306.1997.

Abstract

Duplicate blood samples collected in EDTA and acid-citrate-dextrose (ACD) were compared by cytomegalovirus (CMV) pp65 antigenemia and CMV infectivity on the day of sample collection and after 1 and 2 days of storage at 4 degrees C. No significant difference was detected between EDTA and ACD. However, CMV antigenemia was more sensitive than culture at all time points tested.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Blood Preservation / instrumentation*
  • Citric Acid
  • Cytomegalovirus / isolation & purification*
  • Edetic Acid
  • Glucose / analogs & derivatives
  • Humans
  • Leukocytes / virology*
  • Viral Load

Substances

  • acid citrate dextrose
  • Citric Acid
  • Edetic Acid
  • Glucose