Congenital constriction band syndrome. Pathophysiology and treatment

Yale J Biol Med. 1993 May-Jun;66(3):143-55.

Abstract

The clinical manifestations of 88 children with congenital constriction band syndrome involvement of the hand were reviewed. Seventy-five of these children had evidence of digital or limb amputations, with 235 upper limb amputations and 138 lower limb amputations. In the hand, digital amputations were most common in the index, middle, and ring fingers, whereas in the foot, amputations of the hallux were most often noted. Band indentation was often present at multiple levels. Proximal bands may be associated with neural compression. Syndactyly was invariably associated with a proximal interdigital sinus or cleft and was frequently associated with distal amputation. Examination of a 27-week gestation stillborn specimen having manifestations of congenital constriction band syndrome demonstrated the intrauterine biologic response to band constriction. The variable clinical manifestations of congenital constriction band syndrome can best be explained as the response of the growing, embryologically defined limb to intrauterine deformation or band-induced compression and ischemia.

Publication types

  • Historical Article

MeSH terms

  • Abnormalities, Multiple / embryology
  • Amniotic Band Syndrome / embryology
  • Amniotic Band Syndrome / history
  • Amniotic Band Syndrome / physiopathology*
  • Amniotic Band Syndrome / surgery
  • Arm / abnormalities
  • Arm / embryology
  • Clubfoot / embryology
  • Fetal Death / pathology
  • Foot Deformities, Congenital / embryology
  • Foot Deformities, Congenital / physiopathology
  • Foot Deformities, Congenital / surgery
  • Hand Deformities, Congenital / embryology
  • Hand Deformities, Congenital / physiopathology*
  • Hand Deformities, Congenital / surgery
  • History, 17th Century
  • History, 19th Century
  • History, 20th Century
  • Humans
  • Infant, Newborn
  • Retrospective Studies
  • Syndactyly / embryology
  • Syndactyly / physiopathology
  • Syndactyly / surgery