Epidemic hemorrhagic fever in Hubei Province, The People's Republic of China: a clinical and serological study

Yale J Biol Med. 1981 Jan-Feb;54(1):41-55.

Abstract

Between July 1975 and April 1980, 71 patients were admitted to the Second Attached Hospital of Hubei Provincial Medical College in Wuchang with the diagnosis of epidemic hemorrhagic fever (EHF). The clinical course among these patients was similar to that described for patients with Korean hemorrhagic fever, and hemorrhagic fever with renal syndrome of the U.S.S.R. The overall mortality was 11.2 percent. Sera obtained from some of these patients as well as from patients admitted to the First Attached Hospital of Hubei Provincial Medical College were tested against an antigen associated with Korean hemorrhagic fever and showed exceedingly high antibody titers. We conclude that EHF in Central China represents the same or a closely related disease process as Korean hemorrhagic fever.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Central Nervous System Diseases / etiology
  • China
  • Delivery of Health Care
  • Female
  • Hemorrhagic Fever with Renal Syndrome / diagnosis*
  • Humans
  • Hypotension / etiology
  • Length of Stay
  • Male
  • Middle Aged
  • Oliguria / etiology
  • Serologic Tests
  • Shock, Hemorrhagic / etiology