Pulmonary granulomas in a patient on MER therapy

Yale J Biol Med. 1977 Nov-Dec;50(6):665-8.

Abstract

A patient with metastatic melanoma developed symmetric miliary infiltrates of the lungs while receiving injections of MER into tumor containing lymph nodes of the groin. Open lung biopsy identified the pulmonary lesions as caseating epithelioid granulomas. After cessation of MER therapy, the pulmonary lesions regressed spontaneously. The possible etiology of this so-far-unreported complication of MER therapy was briefly discussed.

Publication types

  • Case Reports

MeSH terms

  • BCG Vaccine / administration & dosage
  • BCG Vaccine / adverse effects*
  • Female
  • Granuloma / etiology*
  • Granuloma / immunology
  • Humans
  • Lung Diseases / etiology*
  • Lung Diseases / immunology
  • Middle Aged

Substances

  • BCG Vaccine