Tyrosine transaminase: development of daily rhythm in liver of neonatal rat

Science. 1968 Nov 29;162(3857):999-1001. doi: 10.1126/science.162.3857.999.

Abstract

The development of the 24-hour rhythm in tyrosine transaminase activity was studied in the liver of the neonatal rat. A recognizable rhythm appears within 48 hours after birth, but it is opposite in phase to that observed in the adult rat. The reversal of the adult pattern occurs 21 to 23 days after birth and may represent a response to a change both in the eating pattern and in the amount of protein eaten.

MeSH terms

  • Animals
  • Animals, Newborn / metabolism*
  • Circadian Rhythm*
  • Dietary Proteins
  • Feeding Behavior
  • Female
  • Growth
  • Liver / enzymology*
  • Periodicity
  • Phenylpyruvic Acids / metabolism
  • Pituitary-Adrenal System
  • Rats
  • Tyrosine Transaminase / metabolism*

Substances

  • Dietary Proteins
  • Phenylpyruvic Acids
  • Tyrosine Transaminase