WONOEP appraisal: Network concept from an imaging perspective

Epilepsia. 2019 Jul;60(7):1293-1305. doi: 10.1111/epi.16067. Epub 2019 Jun 9.

Abstract

Neuroimaging techniques applied to a variety of organisms-from zebrafish, to rodents to humans-can offer valuable insights into neuronal network properties and their dysfunction in epilepsy. A wide range of imaging methods used to monitor neuronal circuits and networks during evoked seizures in animal models and advances in functional magnetic resonance imaging (fMRI) applied to patients with epilepsy were discussed during the XIV Workshop on Neurobiology of Epilepsy (XIV WONOEP) organized in 2017 by the Neurobiology Commission of the International League Against Epilepsy (ILAE). We review the growing number of technological approaches developed, as well as the current state of knowledge gained from studies applying these advanced imaging approaches to epilepsy research.

Keywords: calcium imaging; epileptic networks; fMRI; graph theory; neuroimaging.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Brain / diagnostic imaging*
  • Drug Resistant Epilepsy / diagnostic imaging
  • Education
  • Epilepsy / diagnostic imaging*
  • Epilepsy, Temporal Lobe / diagnostic imaging
  • Functional Neuroimaging* / methods
  • Humans