Clamping Together Hemidesmosomes and Latching Them in Place

Titus J Boggon

doi:10.1016/j.str.2019.05.005

Clamping Together Hemidesmosomes and Latching Them in Place

Structure. 2019 Jun 4;27(6):881-883. doi: 10.1016/j.str.2019.05.005.

Author

Titus J Boggon¹

Affiliation

¹ Department of Pharmacology, Yale University, New Haven, CT 06510, USA; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06510, USA; Yale Cancer Center, Yale University, New Haven, CT 06510, USA. Electronic address: titus.boggon@yale.edu.

PMID: 31167122
DOI: 10.1016/j.str.2019.05.005

Abstract

Integrin adhesion receptors are critical for cell adhesion to the extracellular matrix. In this issue of Structure, Manso et al. (2019) provide new insights into formation of specialized integrin adhesion structures, termed hemidesmosomes, that anchor epithelial cells to the basement membrane.

Publication types

Research Support, N.I.H., Extramural
Comment

MeSH terms

Cell Adhesion
Constriction
Hemidesmosomes*
Humans
Integrin alpha6beta4
Pemphigoid, Bullous*

Substances

Integrin alpha6beta4