Anti-Müllerian Hormone and Its Predictive Utility in Assisted Reproductive Technologies Outcomes

Clin Obstet Gynecol. 2019 Jun;62(2):238-256. doi: 10.1097/GRF.0000000000000436.

Abstract

Anti-Müllerian hormone (AMH) has become one of the most informative biochemical markers of the ovary and is considered the earliest and most sensitive marker of reproductive aging. The accuracy of AMH in predicting ovarian response to controlled ovarian stimulation has led to AMH-based prognostication counseling and individualization of assisted reproductive technology (ART) stimulation protocols to optimize ovarian response and minimize hyperstimulation risks. Although AMH is considered a good predictor of quantitative ART outcomes, its correlation with qualitative ART outcomes is still controversial. The aim of this review is to provide an updated overview of the clinical utility of AMH in predicting ART outcomes.

Publication types

  • Review

MeSH terms

  • Abortion, Spontaneous / blood
  • Anti-Mullerian Hormone / blood*
  • Biomarkers / blood
  • Dose-Response Relationship, Drug
  • Embryo, Mammalian
  • Female
  • Gonadotropins / administration & dosage
  • Humans
  • Live Birth
  • Oocytes / cytology
  • Ovarian Hyperstimulation Syndrome / blood
  • Ovarian Hyperstimulation Syndrome / diagnosis
  • Ovarian Reserve
  • Ovulation Induction
  • Pregnancy
  • Reproductive Techniques, Assisted*

Substances

  • Biomarkers
  • Gonadotropins
  • Anti-Mullerian Hormone