Accelerating cancer without mutations

Elife. 2019 Mar 21:8:e45809. doi: 10.7554/eLife.45809.

Abstract

Mice get melanoma faster when they have common, inherited variants in a few genes that control cell-wide changes but also respond to the environment.

Keywords: RNA-binding protein; cancer; cancer biology; melanoma; modifier genes; mouse; ribosomes; ultraviolet radiation.

Publication types

  • Comment

MeSH terms

  • Animals
  • Melanoma*
  • Mice
  • Mutation
  • Skin Neoplasms*
  • Ultraviolet Rays