Induction of sterile type 2 inflammation

Dimitri A de Kouchkovsky; Sourav Ghosh; Carla V Rothlin

doi:10.1038/s41563-019-0300-0

Induction of sterile type 2 inflammation

Nat Mater. 2019 Mar;18(3):193-194. doi: 10.1038/s41563-019-0300-0.

Authors

Dimitri A de Kouchkovsky¹, Sourav Ghosh^{2

3}, Carla V Rothlin^{4

5}

Affiliations

¹ Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.
² Department of Pharmacology, Yale University, New Haven, CT, USA. sourav.ghosh@yale.edu.
³ Department of Neurology, Yale University, New Haven, CT, USA. sourav.ghosh@yale.edu.
⁴ Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA. carla.rothlin@yale.edu.
⁵ Department of Pharmacology, Yale University, New Haven, CT, USA. carla.rothlin@yale.edu.

Abstract

Microparticle debris from prosthetic implants has been shown to induce a type 2 inflammatory response through a Burton’s tyrosine kinase-dependent signaling pathway.

Publication types

Comment

MeSH terms

Agammaglobulinaemia Tyrosine Kinase
Humans
Inflammation
Interleukin-33*
Macrophages

Substances

Interleukin-33
Agammaglobulinaemia Tyrosine Kinase

Abstract

Publication types

MeSH terms

Substances

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