Abstract
Cervical cancer is a malignant epithelial tumor that forms in the uterine cervix. Most cases of cervical cancer are preventable through human papilloma virus (HPV) vaccination, routine screening, and treatment of precancerous lesions. However, due to inadequate screening protocols in many regions of the world, cervical cancer remains the fourth-most common cancer in women globally. The complete NCCN Guidelines for Cervical Cancer provide recommendations for the diagnosis, evaluation, and treatment of cervical cancer. This manuscript discusses guiding principles for the workup, staging, and treatment of early stage and locally advanced cervical cancer, as well as evidence for these recommendations. For recommendations regarding treatment of recurrent or metastatic disease, please see the full guidelines on NCCN.org.
Copyright © 2019 by the National Comprehensive Cancer Network.
MeSH terms
-
Antineoplastic Combined Chemotherapy Protocols / standards
-
Antineoplastic Combined Chemotherapy Protocols / therapeutic use
-
Brachytherapy / methods
-
Brachytherapy / standards
-
Cervix Uteri / diagnostic imaging
-
Cervix Uteri / pathology
-
Cervix Uteri / virology
-
Chemoradiotherapy, Adjuvant / standards
-
Female
-
Fertility Preservation / methods
-
Fertility Preservation / standards
-
Humans
-
Hysterectomy / standards
-
Mass Screening / methods
-
Mass Screening / standards
-
Medical Oncology / methods
-
Medical Oncology / standards*
-
Neoplasm Staging
-
Organ Sparing Treatments / methods
-
Organ Sparing Treatments / standards
-
Papanicolaou Test / standards
-
Papillomaviridae / isolation & purification
-
Papillomaviridae / pathogenicity
-
Papillomavirus Infections / diagnosis
-
Papillomavirus Infections / pathology
-
Papillomavirus Infections / therapy*
-
Papillomavirus Infections / virology
-
Societies, Medical / standards
-
United States
-
Uterine Cervical Neoplasms / diagnosis
-
Uterine Cervical Neoplasms / pathology
-
Uterine Cervical Neoplasms / therapy*
-
Uterine Cervical Neoplasms / virology