Tumor-Infiltrating Lymphocytes-Location for Prognostic Evaluation

Clin Cancer Res. 2019 Mar 1;25(5):1449-1451. doi: 10.1158/1078-0432.CCR-18-3803. Epub 2018 Dec 19.

Abstract

Tumor-infiltrating lymphocytes (TIL) are crucial for the success of immunotherapy, and their density can predict prognosis. It has now been shown that computer-based analysis of the spatial organization of TILs adds prognostic value in early-stage non-small cell lung cancer, possibly improving the treatment algorithm to prevent recurrence.See related article by Corredor et al., p. 1526.

Publication types

  • Research Support, Non-U.S. Gov't
  • Comment

MeSH terms

  • Carcinoma, Non-Small-Cell Lung*
  • Humans
  • Lung Neoplasms*
  • Lymphocytes, Tumor-Infiltrating
  • Neoplasm Recurrence, Local
  • Prognosis