Clinical Probability Tools for Deep Venous Thrombosis, Pulmonary Embolism, and Bleeding

Eileen M Harder; Omkar Desai; Peter S Marshall

doi:10.1016/j.ccm.2018.04.001

Clinical Probability Tools for Deep Venous Thrombosis, Pulmonary Embolism, and Bleeding

Clin Chest Med. 2018 Sep;39(3):473-482. doi: 10.1016/j.ccm.2018.04.001.

Authors

Eileen M Harder¹, Omkar Desai², Peter S Marshall³

Affiliations

¹ Department of Internal Medicine, Yale University School of Medicine, 15 York Street, LCI 101, New Haven, CT 06520, USA.
² Section of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, Yale University School of Medicine, 15 York Street, LCI 101, New Haven, CT 06520, USA.
³ Section of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, Yale University School of Medicine, 15 York Street, LCI 101, New Haven, CT 06520, USA. Electronic address: peter.marshall@yale.edu.

PMID: 30122172
DOI: 10.1016/j.ccm.2018.04.001

Abstract

Overdiagnosis of venous thromboembolism is associated with increasing numbers of patient complications and health care burden. Multiple clinical tools exist to estimate the probability of pulmonary embolism and deep venous thrombosis. When used with d-dimer testing, these can further stratify venous thromboembolism risk to help inform the use of additional diagnostic testing. Although there are similar tools to estimate bleeding risk, these are not as well-validated and lack reliability.

Keywords: Bleeding; Clinical decision tools; Deep vein thrombosis; Diagnosis; Pretest probability; Pulmonary embolus; Venous thromboembolism.

Publication types

Review

MeSH terms

Hemorrhage / diagnosis*
Hemorrhage / pathology
Humans
Probability*
Pulmonary Embolism / diagnosis*
Pulmonary Embolism / pathology
Venous Thromboembolism
Venous Thrombosis / diagnosis*
Venous Thrombosis / pathology