Bazedoxifene/conjugated estrogens in combination with leuprolide for the treatment of endometriosis

Amanda M Hill; Bruce Lessey; Valerie A Flores; Hugh S Taylor

doi:10.1002/ccr3.1501

Bazedoxifene/conjugated estrogens in combination with leuprolide for the treatment of endometriosis

Clin Case Rep. 2018 Apr 6;6(6):990-994. doi: 10.1002/ccr3.1501. eCollection 2018 Jun.

Authors

Amanda M Hill¹, Bruce Lessey², Valerie A Flores¹, Hugh S Taylor¹

Affiliations

¹ Yale School of Medicine Yale New Haven Health New Haven Connecticut.
² Fertility Center of the Carolinas Greenville Health System Greenville South Carolina.

Abstract

Bazedoxifene/conjugated estrogens can be used with leuprolide as effective add-back therapy in premenopausal women with endometriosis without unwanted stimulation of the breasts, CNS (Central Nervous System), or endometrium. Bazedoxifene/conjugated estrogens may be an effective progestin-free alternative to traditional add-back therapies.

Keywords: Bazedoxifene; SERMs; endometriosis; pelvic pain.

Publication types

Case Reports