Facial and limb angioedema with parotitis and Kikuchi-like necrotizing lymphadenitis preceding neuropsychiatric systemic lupus erythematosus in a young African American male

Lupus. 2018 Apr;27(4):676-680. doi: 10.1177/0961203317726379. Epub 2017 Aug 29.

Abstract

Angioedema has been observed in a few cases secondary to systemic lupus erythematosus (SLE). Herein, we report a rare case where a young healthy male initially presented with angioedema, lymphadenopathy and parotitis and later on developed neuropsychiatric manifestations at the very onset of his SLE disease. This case illustrates the importance of prompt clinical consideration of lupus with unusual and atypical preceding manifestations.

Keywords: Kikuchi lymphadenitis; Systemic lupus erythematosus; angioedema; neuropsychiatric lupus; parotitis.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Angioedema / diagnosis
  • Angioedema / drug therapy
  • Angioedema / etiology*
  • Angioedema / immunology
  • Biopsy
  • Histiocytic Necrotizing Lymphadenitis / diagnosis
  • Histiocytic Necrotizing Lymphadenitis / drug therapy
  • Histiocytic Necrotizing Lymphadenitis / etiology*
  • Histiocytic Necrotizing Lymphadenitis / immunology
  • Humans
  • Immunosuppressive Agents / therapeutic use
  • Lupus Erythematosus, Systemic / complications*
  • Lupus Erythematosus, Systemic / diagnosis
  • Lupus Erythematosus, Systemic / drug therapy
  • Lupus Erythematosus, Systemic / immunology
  • Lupus Vasculitis, Central Nervous System / diagnosis
  • Lupus Vasculitis, Central Nervous System / drug therapy
  • Lupus Vasculitis, Central Nervous System / etiology*
  • Lupus Vasculitis, Central Nervous System / immunology
  • Male
  • Parotitis / diagnosis
  • Parotitis / drug therapy
  • Parotitis / etiology*
  • Parotitis / immunology
  • Tomography, X-Ray Computed
  • Treatment Outcome

Substances

  • Immunosuppressive Agents