A modification to improve the reliability of [11 C]CN- production in the GE radiochemistry system

David C Labaree; Jim R Ropchan; Nabeel Nabulsi; Yiyun Huang

doi:10.1002/jlcr.3540

A modification to improve the reliability of [¹¹ C]CN^- production in the GE radiochemistry system

J Labelled Comp Radiopharm. 2017 Oct;60(12):592-595. doi: 10.1002/jlcr.3540. Epub 2017 Sep 21.

Authors

David C Labaree¹, Jim R Ropchan¹, Nabeel Nabulsi¹, Yiyun Huang¹

Affiliation

¹ Yale PET Center, Department of Radiology and Biomedical Imaging, Yale University School of Medicine, New Haven, Connecticut, USA.

PMID: 28833348
DOI: 10.1002/jlcr.3540

Abstract

We report herein a modification to a component of the GE radiochemistry system that increases the yield and reliability of [¹¹ C]CN^- production from [¹¹ C]carbon dioxide.

Keywords: GE radiochemistry system; [11C]cyanide; automation; radiosynthesis.

MeSH terms

Carbon Radioisotopes / chemistry*
Cyanides / chemical synthesis
Cyanides / chemistry*
Isotope Labeling
Radiochemistry / instrumentation*

Substances

Carbon Radioisotopes
Cyanides